Entity Details

Primary name TGM3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08188
EntryNameTGM3_HUMAN
FullNameProtein-glutamine gamma-glutamyltransferase E
TaxID9606
Evidenceevidence at protein level
Length693
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesTGM3

GO terms

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GOName
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0003824 catalytic activity
GO:0005198 structural molecule activity
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0006464 cellular protein modification process
GO:0016746 acyltransferase activity
GO:0018149 peptide cross-linking
GO:0030216 keratinocyte differentiation
GO:0031069 hair follicle morphogenesis
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031424 keratinization
GO:0032991 protein-containing complex
GO:0043163 cell envelope organization
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001102 Transglutaminase, N-terminalDomainDomain
IPR002931 Transglutaminase-likeDomainDomain
IPR008958 Transglutaminase, C-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR013808 Transglutaminase, active siteSiteActive site
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR023608 Protein-glutamine gamma-glutamyltransferase, animalFamilyFamily
IPR036238 Transglutaminase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR036985 Transglutaminase-like superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule
DB01864 5'-Guanosine-Diphosphate-MonothiophosphateDrugbanksmall molecule
DB01972 Guanosine-5'-MonophosphateDrugbanksmall molecule
DB03152 B-2-OctylglucosideDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule