Entity Details

Primary name SCAP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12770
EntryNameSCAP_HUMAN
FullNameSterol regulatory element-binding protein cleavage-activating protein
TaxID9606
Evidenceevidence at protein level
Length1279
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesSCAP

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001666 response to hypoxia
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006955 immune response
GO:0007568 aging
GO:0008203 cholesterol metabolic process
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016021 integral component of membrane
GO:0032868 response to insulin
GO:0032933 SREBP signaling pathway
GO:0032934 sterol binding
GO:0032991 protein-containing complex
GO:0042304 regulation of fatty acid biosynthetic process
GO:0044255 cellular lipid metabolic process
GO:0044877 protein-containing complex binding
GO:0045541 negative regulation of cholesterol biosynthetic process
GO:0045542 positive regulation of cholesterol biosynthetic process
GO:0051082 unfolded protein binding
GO:0090110 COPII-coated vesicle cargo loading

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR000731 Sterol-sensing domainDomainDomain
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR030225 Sterol regulatory element-binding protein cleavage-activating proteinFamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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