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Entity Details
Primary name
CDK8
Entity type
gene
Source
Source Link
Details
PrimaryID
1024
RefseqGene
Symbol
CDK8
Name
cyclin dependent kinase 8
Chromosome
13
Location
13q12.13
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
1998-08-05
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
CDK8_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0004672
protein kinase activity
GO:0004693
cyclin-dependent protein serine/threonine kinase activity
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005730
nucleolus
GO:0006468
protein phosphorylation
GO:0008353
RNA polymerase II CTD heptapeptide repeat kinase activity
GO:0016592
mediator complex
GO:0032991
protein-containing complex
GO:0045944
positive regulation of transcription by RNA polymerase II
GO:0060260
regulation of transcription initiation from RNA polymerase II promoter
GO:0106310
protein serine kinase activity
GO:0106311
protein threonine kinase activity
Diseases
Show/Hide Table
Interactions
247 interactions
Interactor
Partner
Sources
Publications
Link
CDK8
CCNC
BioGRID, DIP, HPRD, IntAct
10024883
10353252
10882111
11416138
11867769
15328539
19047373
19914168
20098423
21806996
23602568
23746844
24981860
25344755
25416956
26186194
26496610
26502155
28514442
29568061
29997244
30695077
7568034
9150135
9710619
details
CDK8
SMAD1
BioGRID, IntAct
19914168
details
CDK8
AURKA
BioGRID, MINT
24412244
details
CDK8
BMPR1A
BioGRID, MINT
24412244
details
CDK8
BUB1
BioGRID, MINT
24412244
details
CDK8
CCND1
BioGRID, MINT
24412244
details
CDK8
CDH1
BioGRID, MINT
24412244
details
CDK8
ERBB2
BioGRID, MINT
24412244
details
CDK8
KRAS
BioGRID, MINT
24412244
details
CDK8
MCC
BioGRID, MINT
24412244
details
CDK8
MLH3
BioGRID, MINT
24412244
details
CDK8
CTDP1
BioGRID, IntAct
19914168
26496610
details
CDK8
SREBF1
BioGRID, DIP
11834832
16799563
details
CDK8
CRYAA2
IntAct
32814053
details
CDK8
CRYAA
IntAct
32814053
details
CDK8
DYNC1H1
IntAct
32814053
details
CDK8
KLK6
IntAct
32814053
details
CDK8
POLR2A
BioGRID, HPRD
11278802
15009212
15328539
22379099
24981860
8700522
9443979
9710619
details
CDK8
TCEA1
BioGRID
10454562
9305922
details
CDK8
ESR1
BioGRID
11867769
details
CDK8
ESR2
BioGRID
11867769
details
CDK8
PARP1
BioGRID
15808511
16204234
details
CDK8
MYC
BioGRID
11673469
details
CDK8
TP53
BioGRID
10024883
details
CDK8
SMAD2
BioGRID
19914168
details
CDK8
SMAD3
BioGRID
19914168
details
CDK8
SMARCA4
BioGRID
22668559
details
CDK8
BCL6
BioGRID
22668559
details
CDK8
SUZ12
BioGRID
22668559
details
CDK8
CDK8
BioGRID
15328539
22379099
23322298
23602568
29568061
details
CDK8
H3C14
BioGRID
22379099
details
CDK8
NRIP1
BioGRID
21868449
details
CDK8
TOP1
BioGRID
12549820
details
CDK8
MBP
BioGRID
15328539
details
CDK8
ERCC3
BioGRID
10993082
details
CDK8
CCNH
BioGRID, HPRD
10993082
details
CDK8
MAML1
BioGRID, HPRD
15546612
details
CDK8
PRMT5
BioGRID
23749998
details
CDK8
WDR77
BioGRID
23749998
details
CDK8
MED10
BioGRID, IntAct
10024883
10198638
11867769
15175163
15989967
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED19
BioGRID, IntAct
15175163
21729782
23563140
24981860
26186194
28514442
29568061
details
CDK8
MED9
BioGRID, HPRD, IntAct
14638676
15175163
20098423
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
CDK19
BioGRID, IntAct
15175163
24981860
26186194
28514442
30695077
details
CDK8
MED14
BioGRID, DIP, IntAct, MINT
10024883
10198638
10882111
11416138
18418385
20098423
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED15
BioGRID, DIP, IntAct, MINT
14657022
18418385
20098423
20720539
23602568
23749998
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED1
BioGRID, DIP, IntAct, MINT
10024883
10198638
10882111
11867769
15989967
18418385
20098423
23322298
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED23
BioGRID, DIP, IntAct, MINT
10353252
11416138
11867769
18418385
20098423
23322298
23602568
25281560
26186194
26496610
28514442
29568061
details
CDK8
MED17
BioGRID, DIP, IntAct
10198638
10882111
11867769
20098423
23602568
23749998
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED7
BioGRID, IntAct, MINT
10353252
10882111
11867769
23602568
24981860
26186194
28514442
29568061
details
CDK8
MED21
BioGRID, HPRD, IntAct, MINT
10024883
10198638
10882111
11867769
23602568
24981860
26496610
28514442
29568061
9315662
9710619
details
CDK8
MED16
BioGRID, DIP, IntAct
10198638
10882111
11867769
20098423
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED13
BioGRID, DIP, IntAct
10198638
10882111
11867769
19047373
20098423
23322298
23602568
23746844
24981860
26186194
26496610
28514442
29568061
30695077
details
CDK8
MED8
BioGRID, HPRD, IntAct
12584197
23602568
24981860
26186194
26344197
26496610
28514442
29568061
details
CDK8
MED6
BioGRID, IntAct
10024883
10198638
10882111
11416138
11867769
14983011
15808511
23602568
24981860
26186194
26344197
26496610
28514442
29568061
details
CDK8
MED20
BioGRID, IntAct
10882111
11867769
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED12
BioGRID, DIP, HPRD, IntAct, MINT
10198638
10882111
11867769
15175163
19047373
20098423
20720539
23322298
23602568
23746844
23749998
24981860
26186194
26496610
27684187
28514442
29568061
30099503
30695077
details
CDK8
MED22
BioGRID, IntAct
20098423
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED31
BioGRID, IntAct, MINT
10024883
10198638
23602568
24981860
26496610
29568061
details
CDK8
MED30
BioGRID, IntAct
18691967
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED24
BioGRID, DIP, IntAct
10024883
10198638
10882111
11867769
20098423
23322298
23602568
24981860
26186194
26344197
26496610
28514442
29568061
details
CDK8
MTBP
BioGRID, IntAct
26496610
29568061
30695077
details
CDK8
E2F1
DIP
18794899
details
CDK8
MED25
BioGRID, DIP, HPRD, IntAct
14638676
14657022
14983011
20098423
25792360
26186194
26496610
28514442
29568061
details
CDK8
KAT2B
BioGRID, IntAct
29568061
9710619
details
CDK8
GTF2F1
BioGRID, IntAct
29568061
9121429
details
CDK8
BRCA1
BioGRID
9159119
details
CDK8
CEBPB
BioGRID
14759369
details
CDK8
CREBBP
BioGRID
9710619
details
CDK8
SMARCB1
BioGRID
9710619
details
CDK8
SMARCC2
BioGRID
9710619
details
CDK8
SMARCC1
BioGRID
9710619
details
CDK8
SMARCA2
BioGRID
9710619
details
CDK8
THRAP3
BioGRID
10198638
details
CDK8
THRA
BioGRID
10198638
details
CDK8
EHMT2
BioGRID
18691967
details
CDK8
SMAD5
BioGRID
19914168
details
CDK8
SMC1A
BioGRID
20720539
details
CDK8
SMC3
BioGRID
20720539
details
CDK8
NIPBL
BioGRID
20720539
details
CDK8
STK38
BioGRID
23749998
details
CDK8
USP7
BioGRID
27934968
details
CDK8
TICRR
BioGRID
30695077
details
CDK8
TOPBP1
BioGRID
30695077
details
CDK8
CDKN2B
HPRD
12007796
details
CDK8
MED26
BioGRID, DIP, HPRD, IntAct
15175163
20098423
21729782
23746844
24981860
details
CDK8
MED29
BioGRID, IntAct
15175163
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
KAT2A
BioGRID, IntAct, MINT
18418385
29568061
details
CDK8
TRRAP
BioGRID, MINT
18418385
details
CDK8
MED13L
BioGRID, IntAct
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED28
BioGRID, IntAct
15175163
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
HNRNPF
BioGRID, IntAct
23602568
details
CDK8
HERC2
BioGRID, IntAct
23602568
details
CDK8
MED27
BioGRID, IntAct
23602568
24981860
26186194
26496610
28514442
29568061
details
CDK8
MED11
BioGRID, IntAct
23602568
24981860
26496610
29568061
details
CDK8
MED18
BioGRID, IntAct, MINT
23602568
24981860
26496610
28514442
29568061
details
CDK8
MED4
BioGRID, IntAct, MINT
23602568
24981860
25281560
26186194
26496610
28514442
29568061
details
CDK8
HIF1A
BioGRID, IntAct
23746844
details
CDK8
CDK9
DIP, IntAct
20098423
23746844
details
CDK8
CCT2
IntAct
19047373
details
CDK8
PRKDC
IntAct
19047373
details
CDK8
CELF1
BioGRID, IntAct
26496610
details
CDK8
GET4
BioGRID, IntAct
26496610
details
CDK8
BUD13
BioGRID, IntAct
26496610
details
CDK8
ZNF131
BioGRID, IntAct
26496610
29568061
details
CDK8
TAF1
BioGRID, IntAct
26496610
details
CDK8
BAG6
BioGRID, IntAct
26496610
details
CDK8
GCFC2
BioGRID, IntAct
26496610
details
CDK8
POLR1D
BioGRID, IntAct
26496610
details
CDK8
RBM45
BioGRID, IntAct
26496610
details
CDK8
TBX3
BioGRID, IntAct
26496610
details
CDK8
DENND4C
BioGRID, IntAct
26496610
details
CDK8
SRGAP1
BioGRID, IntAct
26496610
details
CDK8
GEMIN5
BioGRID, IntAct
26496610
details
CDK8
SUPT7L
BioGRID, IntAct
26496610
details
CDK8
PCF11
BioGRID, IntAct
26496610
details
CDK8
UBL4A
BioGRID, IntAct
26496610
details
CDK8
WWP1
BioGRID, IntAct
26496610
details
CDK8
POLR2C
BioGRID, IntAct
24981860
26496610
details
CDK8
H3C1
IntAct
26496610
details
CDK8
H3C4
IntAct
26496610
details
CDK8
H3C3
IntAct
26496610
details
CDK8
H3C6
IntAct
26496610
details
CDK8
H3C11
IntAct
26496610
details
CDK8
H3C8
IntAct
26496610
details
CDK8
H3C12
IntAct
26496610
details
CDK8
H3C10
IntAct
26496610
details
CDK8
H3C2
IntAct
26496610
details
CDK8
H3C7
IntAct
26496610
details
CDK8
RBM4
BioGRID, IntAct
26496610
details
CDK8
MED12L
BioGRID, IntAct
24981860
26186194
28514442
29568061
details
CDK8
CDK16
BioGRID, IntAct
26186194
28514442
details
CDK8
PPP1R12A
BioGRID, IntAct
26186194
28514442
details
CDK8
LZIC
BioGRID, IntAct
28514442
details
CDK8
SREBF2
DIP
16799563
details
CDK8
CCNT1
DIP
20098423
details
CDK8
BRD4
DIP
20098423
details
CDK8
NUDCD1
MINT
29021621
details
CDK8
WDHD1
BioGRID, IntAct
29568061
details
CDK8
MDC1
BioGRID, IntAct
29568061
details
CDK8
NACC1
BioGRID, IntAct
29568061
details
CDK8
RADX
BioGRID, IntAct
29568061
details
CDK8
PPIL2
BioGRID, IntAct
29568061
details
CDK8
NSRP1
IntAct
29568061
details
CDK8
WAC
IntAct
29568061
details
CDK8
ELOB
IntAct
29568061
details
CDK8
BRD8
IntAct
29568061
details
CDK8
GPALPP1
IntAct
29568061
details
CDK8
HAT1
IntAct
29568061
details
CDK8
TAF9B
IntAct
29568061
details
CDK8
MASTL
IntAct
29568061
details
CDK8
SURF6
IntAct
29568061
details
CDK8
CDC16
IntAct
29568061
details
CDK8
DUT
IntAct
29568061
details
CDK8
POLH
IntAct
29568061
details
CDK8
SRRM1
IntAct
29568061
details
CDK8
LARP7
IntAct
29568061
details
CDK8
RNF40
IntAct
29568061
details
CDK8
MEPCE
IntAct
29568061
details
CDK8
RBM28
IntAct
29568061
details
CDK8
ISY1-RAB43
IntAct
29568061
details
CDK8
ISY1
BioGRID, IntAct
29568061
details
CDK8
YEATS2
BioGRID, IntAct
29568061
details
CDK8
BCCIP
BioGRID, IntAct
29568061
details
CDK8
MBIP
BioGRID, IntAct
29568061
details
CDK8
XAB2
BioGRID, IntAct
29568061
details
CDK8
KAT14
BioGRID, IntAct
29568061
details
CDK8
WDR61
BioGRID, IntAct
29568061
details
CDK8
BRIP1
BioGRID, IntAct
29568061
details
CDK8
SLC4A1AP
BioGRID, IntAct
29568061
details
CDK8
NUP205
BioGRID, IntAct
29568061
details
CDK8
PNISR
BioGRID, IntAct
29568061
details
CDK8
PAF1
BioGRID, IntAct
29568061
details
CDK8
ZZZ3
BioGRID, IntAct
29568061
details
CDK8
FTSJ3
BioGRID, IntAct
29568061
details
CDK8
SUGP2
BioGRID, IntAct
29568061
details
CDK8
CTR9
BioGRID, IntAct
29568061
details
CDK8
PPP4R3A
BioGRID, IntAct
29568061
details
CDK8
MYSM1
BioGRID, IntAct
29568061
details
CDK8
RNF20
BioGRID, IntAct
29568061
details
CDK8
PCID2
BioGRID, IntAct
29568061
details
CDK8
ARID4B
BioGRID, IntAct
29568061
details
CDK8
CDC37
BioGRID, IntAct
29568061
details
CDK8
ELOA
BioGRID, IntAct
29568061
details
CDK8
POLA2
BioGRID, IntAct
29568061
details
CDK8
GNL2
BioGRID, IntAct
29568061
details
CDK8
TP53BP1
BioGRID, IntAct, UniProt
29568061
29656893
details
CDK8
WDR5
BioGRID, IntAct
29568061
details
CDK8
MFAP1
BioGRID, IntAct
29568061
details
CDK8
KPNA1
BioGRID, IntAct
29568061
details
CDK8
MNAT1
BioGRID, IntAct
29568061
details
CDK8
HDGF
BioGRID, IntAct
29568061
details
CDK8
PRIM2
BioGRID, IntAct
29568061
details
CDK8
GTF2E1
BioGRID, IntAct
29568061
details
CDK8
CDK11B
BioGRID, IntAct
29568061
details
CDK8
HIVEP1
BioGRID, IntAct
29568061
details
CDK8
POLA1
BioGRID, IntAct
29568061
details
CDK8
TADA3
BioGRID, IntAct
29568061
details
CDK8
TADA2A
BioGRID, IntAct
20508642
29568061
details
CDK8
PES1
BioGRID, IntAct
29568061
details
CDK8
SBNO1
BioGRID, IntAct
29568061
details
CDK8
TAF6L
BioGRID, IntAct
29568061
details
CDK8
GTF3C3
BioGRID, IntAct
29568061
details
CDK8
GTF3C5
BioGRID, IntAct
29568061
details
CDK8
ZSCAN21
BioGRID, IntAct
29568061
details
CDK8
LAS1L
BioGRID, IntAct
29568061
details
CDK8
ZNF281
BioGRID, IntAct
29568061
details
CDK8
GTF3C4
BioGRID, IntAct
29568061
details
CDK8
RAD18
BioGRID, IntAct
29568061
details
CDK8
EHMT1
BioGRID, IntAct
29568061
details
CDK8
ESF1
BioGRID, IntAct
29568061
details
CDK8
POLR3C
BioGRID, IntAct
29568061
details
CDK8
MTA3
BioGRID, IntAct
29568061
details
CDK8
ZNF830
BioGRID, IntAct
29568061
details
CDK8
MGA
BioGRID, IntAct
29568061
details
CDK8
WAPL
BioGRID, IntAct
29568061
details
CDK8
ZMYM4
BioGRID, IntAct
29568061
details
CDK8
RIF1
BioGRID, IntAct
29568061
details
CDK8
DDX10
BioGRID, IntAct
29568061
details
CDK8
GTF3C1
BioGRID, IntAct
29568061
details
CDK8
PRIM1
BioGRID, IntAct
29568061
details
CDK8
MSH2
BioGRID, IntAct
29568061
details
CDK8
GTF2E2
BioGRID, IntAct
29568061
details
CDK8
WIZ
BioGRID, IntAct
29568061
details
CDK8
KIF4A
BioGRID, IntAct
29568061
details
CDK8
AQR
BioGRID, IntAct
29568061
details
CDK8
PPM1G
BioGRID, IntAct
29568061
details
CDK8
RPA2
IntAct
29568061
details
CDK8
RBM33
IntAct
29568061
details
CDK8
SEC13
IntAct
29568061
details
CDK8
HSPA1A
IntAct
29568061
details
CDK8
HSPA1B
IntAct
29568061
details
CDK8
SEC16A
BioGRID, IntAct
29568061
details
CDK8
H3-5
BioGRID
26496610
details
CDK8
FBXW7
BioGRID
25720964
details
CDK8
HNRNPD
BioGRID
26318153
details
CDK8
BRPF3
BioGRID
31753913
details
CDK8
ACAD11
BioGRID
24981860
details
CDK8
POLR2E
BioGRID
24981860
details
CDK8
POLR2H
BioGRID
24981860
details
CDK8
POLR2I
BioGRID
24981860
details
CDK8
POLR2B
BioGRID
24981860
details
CDK8
ANKRD37
IntAct
23746844
details
CDK8
MAGI1
IntAct
23746844
details
CDK8
UHMK1
IntAct
23746844
details
CDK8
STC2
IntAct
23746844
details
CDK8
CXCR4
IntAct
23746844
details
CDK8
HNRNPL
BioGRID
28611215
details
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