Entity Details

Primary name LILRB4
Entity type gene
Source Source Link

Details

PrimaryID11006
RefseqGene
SymbolLILRB4
Nameleukocyte immunoglobulin like receptor B4
Chromosome19
Location19q13.42
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-12
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsLIRB4_HUMAN

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002507 tolerance induction
GO:0002669 positive regulation of T cell anergy
GO:0002725 negative regulation of T cell cytokine production
GO:0002774 Fc receptor mediated inhibitory signaling pathway
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0019903 protein phosphatase binding
GO:0030293 transmembrane receptor protein tyrosine kinase inhibitor activity
GO:0030547 signaling receptor inhibitor activity
GO:0031623 receptor internalization
GO:0032682 negative regulation of chemokine production
GO:0032689 negative regulation of interferon-gamma production
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032693 negative regulation of interleukin-10 production
GO:0032703 negative regulation of interleukin-2 production
GO:0032714 negative regulation of interleukin-5 production
GO:0032715 negative regulation of interleukin-6 production
GO:0042130 negative regulation of T cell proliferation
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0043409 negative regulation of MAPK cascade
GO:0045584 negative regulation of cytotoxic T cell differentiation
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0045671 negative regulation of osteoclast differentiation
GO:0046007 negative regulation of activated T cell proliferation
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070062 extracellular exosome
GO:0071659 negative regulation of IP-10 production
GO:0098752 integral component of the cytoplasmic side of the plasma membrane
GO:0140105 interleukin-10-mediated signaling pathway
GO:0150102 negative regulation of monocyte activation
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1900181 negative regulation of protein localization to nucleus
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:2000272 negative regulation of signaling receptor activity
GO:2000524 negative regulation of T cell costimulation

Diseases

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Interactions

13 interactions

InteractorPartnerSourcesPublicationsLink
LILRB4PTPN6IntAct18802077 details
LILRB4MKLN1BioGRID, IntAct28514442 details
LILRB4GID8BioGRID, IntAct28514442 details
LILRB4C10orf88BioGRID, IntAct28514442 details
LILRB4GID4BioGRID, IntAct28514442 details
LILRB4ARMC8BioGRID, IntAct28514442 details
LILRB4CD276BioGRID, IntAct28514442 details
LILRB4ATP2B3BioGRID, IntAct28514442 details
LILRB4CD47BioGRID, IntAct28514442 details
LILRB4ATP2B2BioGRID, IntAct28514442 details
LILRB4ATP2B4BioGRID, IntAct28514442 details
LILRB4PTPRDBioGRID, IntAct28514442 details
LILRB4HLA-AIntAct28514442 details