Entity Details

Primary name DMD
Entity type gene
Source Source Link

Details

PrimaryID1756
RefseqGeneNG_012232
SymbolDMD
Namedystrophin
ChromosomeX
LocationXp21.2-p21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDMD_HUMAN

GO terms

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GOName
GO:0002027 regulation of heart rate
GO:0002162 dystroglycan binding
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0007517 muscle organ development
GO:0008270 zinc ion binding
GO:0008307 structural constituent of muscle
GO:0009986 cell surface
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010976 positive regulation of neuron projection development
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0014819 regulation of skeletal muscle contraction
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016013 syntrophin complex
GO:0017022 myosin binding
GO:0017166 vinculin binding
GO:0030018 Z disc
GO:0030049 muscle filament sliding
GO:0030055 cell-substrate junction
GO:0030175 filopodium
GO:0031527 filopodium membrane
GO:0032991 protein-containing complex
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0034613 cellular protein localization
GO:0034622 cellular protein-containing complex assembly
GO:0035633 maintenance of blood-brain barrier
GO:0035994 response to muscle stretch
GO:0042383 sarcolemma
GO:0043034 costamere
GO:0043043 peptide biosynthetic process
GO:0044306 neuron projection terminus
GO:0044458 motile cilium assembly
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045666 positive regulation of neuron differentiation
GO:0046716 muscle cell cellular homeostasis
GO:0050998 nitric-oxide synthase binding
GO:0060048 cardiac muscle contraction
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity
GO:0086001 cardiac muscle cell action potential
GO:0090287 regulation of cellular response to growth factor stimulus
GO:1901385 regulation of voltage-gated calcium channel activity
GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation
GO:2000651 positive regulation of sodium ion transmembrane transporter activity

Diseases

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Interactions

87 interactions

InteractorPartnerSourcesPublicationsLink
DMDDTNABioGRID, HPRD, IntAct, MINT10767429 16448387 28514442 9356463 9701558 details
DMDDTNBBioGRID, HPRD, IntAct, MINT10545507 16448387 25416956 28514442 31515488 32296183 9395493 details
DMDSNTB1BioGRID, HPRD, IntAct28514442 7844150 8576247 details
DMDSNTB2BioGRID, HPRD, IntAct22937058 28514442 8576247 details
DMDDISC1BioGRID, IntAct17043677 31413325 details
DMDDAG1BioGRID, HPRD, IntAct10355629 10932245 19109891 7592992 details
DMDMAP3K5BioGRID, IntAct20936779 details
DMDCDC25ABioGRID, IntAct21988832 details
DMDHAUS1BioGRID, IntAct25416956 28514442 details
DMDCTNNAL1BioGRID, IntAct21115837 25416956 28514442 32296183 details
DMDPICK1BioGRID, IntAct32296183 details
DMDHNF4ABioGRID, IntAct25910212 details
DMDSNTA1BioGRID, HPRD, IntAct10747910 11571312 18468998 28514442 7890602 8576247 9412493 details
DMDSNTG2BioGRID, HPRD, IntAct10747910 28514442 details
DMDTRAF3IP1BioGRID, IntAct17043677 31413325 details
DMDACTA1BioGRID, HPRD11259305 1544421 details
DMDAPPBioGRID21832049 details
DMDSNTG1BioGRID, HPRD10747910 11352924 details
DMDTRIM63BioGRID33106653 details
DMDCADPSHPRD12659812 details
DMDCADPS2HPRD12659812 details
DMDKRT19HPRD, IntAct16000376 details
DMDANK2IntAct19109891 details
DMDUTRNBioGRID, HPRD, IntAct10767429 28514442 details
DMDKCNJ12BioGRID, HPRD15024025 details
DMDKCNJ4BioGRID15024025 details
DMDTERF1BioGRID20811636 details
DMDTERF2BioGRID20811636 details
DMDNFX1BioGRID17267499 details
DMDMARK2BioGRID19945424 details
DMDCAVIN1BioGRID22937058 details
DMDAHNAKBioGRID22937058 details
DMDNOS1BioGRID7545544 details
DMDGANBioGRID26460568 details
DMDPRNPBioGRID11032878 details
DMDPGM5HPRD10867799 7890770 details
DMDDGKZHPRD11352924 details
DMDSGCZHPRD12189167 details
DMDDMDHPRD10801490 details
DMDACTC1HPRD11997265 details
DMDFASLGHPRD11741599 details
DMDKRT8HPRD, IntAct16000376 details
DMDALBBioGRID, IntAct15174051 details
DMDARRB1BioGRID, IntAct17620599 details
DMDNUP58BioGRID, IntAct26496610 details
DMDKIF15BioGRID, IntAct26496610 details
DMDLPAR6BioGRID, IntAct26186194 28514442 details
DMDLRRC8EBioGRID, IntAct28514442 details
DMDPALS2BioGRID, IntAct28514442 details
DMDWDR54BioGRID, IntAct28514442 details
DMDHAUS4BioGRID, IntAct28514442 details
DMDOSBPL1ABioGRID, IntAct28514442 details
DMDTRIM41BioGRID, IntAct28514442 details
DMDSIRT2BioGRID, IntAct28514442 details
DMDLONRF3BioGRID, IntAct28514442 details
DMDKIF23BioGRID, IntAct28514442 details
DMDCTNNA1BioGRID, IntAct26344197 28514442 details
DMDIFIT5BioGRID, IntAct28514442 details
DMDABCA1DIP25170080 details
DMDPRKCSHBioGRID, IntAct30021884 details
DMDSF3B2BioGRID, IntAct30021884 details
DMDH3-4BioGRID, IntAct30021884 details
DMDADRA1DIntAct26617989 27382054 details
DMDTIAM1BioGRID, IntAct32203420 details
DMDZGPATBioGRID, MINT24981860 details
DMDCD81IntAct32900848 details
DMDNEDD4BioGRID22939629 details
DMDXPO1BioGRID26673895 details
DMDMCM2BioGRID25963833 details
DMDTNS2BioGRID27432908 27880917 28675297 details
DMDTNS1BioGRID27880917 details
DMDTNS3BioGRID27880917 details
DMDRESTBioGRID27976729 details
DMDHDAC2BioGRID30737378 details
DMDAGRNBioGRID29872149 details
DMDPAK5BioGRID31219614 details
DMDPLEKHA4BioGRID31091453 details
DMDANLNBioGRID31586073 details
DMDKIF14BioGRID31586073 details
DMDBCAR1BioGRID33001583 details
DMDRNF11BioGRID31985874 details
DMDCUL4ABioGRID32235678 details
DMDARF6BioGRID34079125 details
DMDLAMTOR1BioGRID34079125 details
DMDLYNBioGRID34079125 details
DMDMARCKSBioGRID34079125 details
DMDTRIM25BioGRID29117863 details