Entity Details

Primary name SPRED2
Entity type gene
Source Source Link

Details

PrimaryID200734
RefseqGene
SymbolSPRED2
Namesprouty related EVH1 domain containing 2
Chromosome2
Location2p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-04-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsSPRE2_HUMAN

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0005173 stem cell factor receptor binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007275 multicellular organism development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0030291 protein serine/threonine kinase inhibitor activity
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030658 transport vesicle membrane
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0090311 regulation of protein deacetylation
GO:1902747 negative regulation of lens fiber cell differentiation

Diseases

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Interactions

68 interactions

InteractorPartnerSourcesPublicationsLink
SPRED2ZDHHC17BioGRID, IntAct24705354 details
SPRED2TOP3BBioGRID, IntAct25416956 29892012 details
SPRED2SPG21BioGRID, IntAct25416956 31515488 32296183 details
SPRED2ZNF837BioGRID, IntAct32296183 details
SPRED2KRTAP2-3BioGRID, IntAct32296183 details
SPRED2KRTAP2-4BioGRID, IntAct32296183 details
SPRED2QARS1BioGRID, IntAct32296183 details
SPRED2KRTAP12-2BioGRID, IntAct32296183 details
SPRED2TSNAXBioGRID, IntAct32296183 details
SPRED2ZNF250BioGRID, IntAct32296183 details
SPRED2NCS1BioGRID, IntAct32296183 details
SPRED2ZNF575BioGRID, IntAct32296183 details
SPRED2ZNF417BioGRID, IntAct32296183 details
SPRED2ZNF414BioGRID, IntAct32296183 details
SPRED2RBM48BioGRID, IntAct32296183 details
SPRED2NDUFB7BioGRID, IntAct32296183 details
SPRED2MDFIBioGRID, IntAct32296183 details
SPRED2AQP1BioGRID, IntAct32296183 details
SPRED2LCE1CBioGRID, IntAct32296183 details
SPRED2VSNL1BioGRID, IntAct32296183 details
SPRED2KPRPBioGRID, IntAct32296183 details
SPRED2LCE2BBioGRID, IntAct32296183 details
SPRED2LCE5ABioGRID, IntAct32296183 details
SPRED2KCNIP1BioGRID, IntAct32296183 details
SPRED2RPS6KA6BioGRID, IntAct32296183 details
SPRED2RPS6KA3BioGRID, IntAct28514442 32814053 details
SPRED2APBB2IntAct32814053 details
SPRED2CALRIntAct32814053 details
SPRED2CHATIntAct32814053 details
SPRED2DLSTIntAct32814053 details
SPRED2DNM2IntAct32814053 details
SPRED2FGFR3IntAct32814053 details
SPRED2GFAPIntAct32814053 details
SPRED2GLE1IntAct32814053 details
SPRED2GRNIntAct32814053 details
SPRED2LMNAIntAct32814053 details
SPRED2NDUFV2IntAct32814053 details
SPRED2NOS3IntAct32814053 details
SPRED2PRPS1IntAct32814053 details
SPRED2WFS1IntAct32814053 details
SPRED2KIF1BIntAct32814053 details
SPRED2RNF11IntAct32814053 details
SPRED2NEK7IntAct32814053 details
SPRED2SPRED1IntAct32814053 details
SPRED2HTTIntAct32814053 details
SPRED2NBR1BioGRID19822672 30771306 details
SPRED2SQSTM1BioGRID19822672 27028858 30771306 details
SPRED2MAP1LC3ABioGRID27028858 details
SPRED2CTSDBioGRID30771306 details
SPRED2MYO15BBioGRID32296183 details
SPRED2CBLMINT17094949 details
SPRED2CLUIntAct31413325 details
SPRED2TESK1BioGRID17974561 details
SPRED2KITHPRD12646235 14981116 details
SPRED2RHOAHPRD15184877 details
SPRED2PDP1BioGRID, IntAct28514442 details
SPRED2PRTFDC1BioGRID, IntAct28514442 details
SPRED2DPP9BioGRID, IntAct28514442 details
SPRED2RPS6KA2BioGRID, IntAct28514442 details
SPRED2GNG5BioGRID, IntAct28514442 details
SPRED2GNAQBioGRID, IntAct28514442 details
SPRED2STOMBioGRID, IntAct28514442 details
SPRED2KRASBioGRID30639242 34079125 details
SPRED2FBXW8BioGRID31343991 details
SPRED2RHOBBioGRID34079125 details
SPRED2ELAVL1BioGRID19322201 details
SPRED2MTDHBioGRID22199357 details
SPRED2DDX58BioGRID32513696 details