Entity Details

Primary name EREG
Entity type gene
Source Source Link

Details

PrimaryID2069
RefseqGene
SymbolEREG
Nameepiregulin
Chromosome4
Location4q13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEREG_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001525 angiogenesis
GO:0001550 ovarian cumulus expansion
GO:0001556 oocyte maturation
GO:0001819 positive regulation of cytokine production
GO:0005154 epidermal growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0007143 female meiotic nuclear division
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009299 mRNA transcription
GO:0009653 anatomical structure morphogenesis
GO:0009887 animal organ morphogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0030216 keratinocyte differentiation
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0030728 ovulation
GO:0032755 positive regulation of interleukin-6 production
GO:0038128 ERBB2 signaling pathway
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042060 wound healing
GO:0042327 positive regulation of phosphorylation
GO:0042700 luteinizing hormone signaling pathway
GO:0043434 response to peptide hormone
GO:0043616 keratinocyte proliferation
GO:0045089 positive regulation of innate immune response
GO:0045740 positive regulation of DNA replication
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 positive regulation of mitotic nuclear division
GO:0045860 positive regulation of protein kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048146 positive regulation of fibroblast proliferation
GO:0048160 primary follicle stage
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051151 negative regulation of smooth muscle cell differentiation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0061024 membrane organization
GO:2000145 regulation of cell motility

Diseases

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Interactions

11 interactions

InteractorPartnerSourcesPublicationsLink
EREGNINJ2BioGRID, IntAct32296183 details
EREGOLFM4BioGRID, IntAct32296183 details
EREGCXCL9BioGRID, IntAct32296183 details
EREGMS4A13BioGRID, IntAct32296183 details
EREGEGFRBioGRID, HPRD, IntAct28988771 9419975 details
EREGERBB4BioGRID, HPRD9419975 details
EREGTMX4BioGRID, IntAct26186194 28514442 details
EREGRAB4ABioGRID, IntAct26186194 28514442 details
EREGLGALS1BioGRID, IntAct26186194 28514442 details
EREGEGFIntAct28988771 details
EREGNRG1IntAct28988771 details