Entity Details

Primary name F2RL1
Entity type gene
Source Source Link

Details

PrimaryID2150
RefseqGene
SymbolF2RL1
NameF2R like trypsin receptor 1
Chromosome5
Location5q13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPAR2_HUMAN

GO terms

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GOName
GO:0001965 G-protein alpha-subunit binding
GO:0002286 T cell activation involved in immune response
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0002720 positive regulation of cytokine production involved in immune response
GO:0003104 positive regulation of glomerular filtration
GO:0004930 G protein-coupled receptor activity
GO:0005102 signaling receptor binding
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007596 blood coagulation
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015057 thrombin-activated receptor activity
GO:0030193 regulation of blood coagulation
GO:0030335 positive regulation of cell migration
GO:0030836 positive regulation of actin filament depolymerization
GO:0031143 pseudopodium
GO:0031274 positive regulation of pseudopodium assembly
GO:0031681 G-protein beta-subunit binding
GO:0032682 negative regulation of chemokine production
GO:0032722 positive regulation of chemokine production
GO:0032729 positive regulation of interferon-gamma production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032930 positive regulation of superoxide anion generation
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
GO:0035025 positive regulation of Rho protein signal transduction
GO:0038023 signaling receptor activity
GO:0042119 neutrophil activation
GO:0042311 vasodilation
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043311 positive regulation of eosinophil degranulation
GO:0043547 positive regulation of GTPase activity
GO:0045087 innate immune response
GO:0045217 cell-cell junction maintenance
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046328 regulation of JNK cascade
GO:0046329 negative regulation of JNK cascade
GO:0046330 positive regulation of JNK cascade
GO:0050900 leukocyte migration
GO:0050921 positive regulation of chemotaxis
GO:0050927 positive regulation of positive chemotaxis
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051607 defense response to virus
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0061028 establishment of endothelial barrier
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070661 leukocyte proliferation
GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0097029 mature conventional dendritic cell differentiation
GO:1900135 positive regulation of renin secretion into blood stream
GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production

Diseases

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Interactions

91 interactions

InteractorPartnerSourcesPublicationsLink
F2RL1COPS5BioGRID, HPRD, UniProt16410250 details
F2RL1TMED2UniProt17693410 21219331 details
F2RL1HSPA1AMINT28298427 details
F2RL1HSPA1BBioGRID, MINT28298427 details
F2RL1ATP2A2BioGRID, MINT28298427 details
F2RL1PRNPBioGRID, MINT28298427 details
F2RL1ABHD14ABioGRID, MINT28298427 details
F2RL1ADCY2BioGRID, MINT28298427 details
F2RL1ARL6IP1BioGRID, MINT28298427 details
F2RL1ABCC8BioGRID, MINT28298427 details
F2RL1ATP2B1BioGRID, MINT28298427 details
F2RL1ATP2C1BioGRID, MINT28298427 details
F2RL1BSGBioGRID, MINT28298427 details
F2RL1CANXBioGRID, MINT28298427 details
F2RL1CNN3BioGRID, MINT28298427 details
F2RL1CRLS1BioGRID, MINT28298427 details
F2RL1CTNNA1BioGRID, MINT28298427 details
F2RL1CD63BioGRID, MINT28298427 details
F2RL1CD81BioGRID, MINT28298427 details
F2RL1MORN4BioGRID, MINT28298427 details
F2RL1SLC18B1BioGRID, MINT28298427 details
F2RL1CAPNS1BioGRID, MINT28298427 details
F2RL1NAT14BioGRID, MINT28298427 details
F2RL1HLA-EBioGRID, MINT28298427 details
F2RL1KLC1BioGRID, MINT28298427 details
F2RL1KDELR1BioGRID, MINT28298427 details
F2RL1ICAM2BioGRID, MINT28298427 details
F2RL1P4HTMBioGRID, MINT28298427 details
F2RL1HERPUD1BioGRID, MINT28298427 details
F2RL1HMOX2BioGRID, MINT28298427 details
F2RL1QSER1BioGRID, MINT28298427 details
F2RL1GJC2BioGRID, MINT28298427 details
F2RL1GJB6BioGRID, MINT28298427 details
F2RL1ERGIC3BioGRID, MINT28298427 details
F2RL1OSTCBioGRID, MINT28298427 details
F2RL1CLPTM1BioGRID, MINT28298427 details
F2RL1SLC32A1BioGRID, MINT28298427 details
F2RL1NBPF15BioGRID, MINT28298427 details
F2RL1SLC12A5BioGRID, MINT28298427 details
F2RL1SLC1A4BioGRID, MINT28298427 details
F2RL1SCN1BBioGRID, MINT28298427 details
F2RL1RGRBioGRID, MINT28298427 details
F2RL1RTN4BioGRID, MINT28298427 details
F2RL1RTN1BioGRID, MINT28298427 details
F2RL1R3HDM1BioGRID, MINT28298427 details
F2RL1PSMC3BioGRID, MINT28298427 details
F2RL1PRRT2BioGRID, MINT28298427 details
F2RL1PHLDA1BioGRID, MINT28298427 details
F2RL1PTDSS2BioGRID, MINT28298427 details
F2RL1PIGUBioGRID, MINT28298427 details
F2RL1SLC31A2BioGRID, MINT28298427 details
F2RL1SLC39A13BioGRID, MINT28298427 details
F2RL1SLC43A2BioGRID, MINT28298427 details
F2RL1SDHDBioGRID, MINT28298427 details
F2RL1SYNGR2BioGRID, MINT28298427 details
F2RL1MFSD10BioGRID, MINT28298427 details
F2RL1SLC35A1BioGRID, MINT28298427 details
F2RL1TMBIM1BioGRID, MINT28298427 details
F2RL1TMED1BioGRID, MINT28298427 details
F2RL1TMEM161ABioGRID, MINT28298427 details
F2RL1TMEM62BioGRID, MINT28298427 details
F2RL1WFS1BioGRID, MINT28298427 details
F2RL1TMX2BioGRID, MINT28298427 details
F2RL1PPM1JBioGRID, MINT28298427 details
F2RL1YIPF6BioGRID, MINT28298427 details
F2RL1YIPF1BioGRID, MINT28298427 details
F2RL1DNMT3LBioGRID24952347 details
F2RL1LMNABioGRID24623722 details
F2RL1CBLHPRD, UniProt15708858 details
F2RL1TLR4UniProt18622013 details
F2RL1TMED10UniProt21219331 details
F2RL1F3DIP16959886 details
F2RL1BIRC5BioGRID20826780 details
F2RL1PLGHPRD10978167 12604689 9020112 details
F2RL1PRTN3HPRD10978167 details
F2RL1ST14HPRD10831593 details
F2RL1CTSGHPRD10978167 details
F2RL1F2HPRD10978167 details
F2RL1ELANEHPRD10978167 details
F2RL1CAPN1HPRD10978167 details
F2RL1CAPN2HPRD10978167 details
F2RL1GPRASP1HPRD15452121 details
F2RL1C19orf25BioGRID, IntAct28514442 details
F2RL1INTS12BioGRID, IntAct28514442 details
F2RL1HSDL2BioGRID, IntAct28514442 details
F2RL1SLMAPBioGRID, IntAct26186194 28514442 details
F2RL1GEMIN4BioGRID26186194 details
F2RL1ZW10BioGRID26186194 details
F2RL1RINT1BioGRID26186194 details
F2RL1GEMIN6BioGRID26186194 details
F2RL1MOV10BioGRID22658674 details