Entity Details

Primary name SHANK2
Entity type gene
Source Source Link

Details

PrimaryID22941
RefseqGeneNG_042866
SymbolSHANK2
NameSH3 and multiple ankyrin repeat domains 2
Chromosome11
Location11q13.3-q13.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSHAN2_HUMAN

GO terms

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GOName
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007416 synapse assembly
GO:0007612 learning
GO:0008284 positive regulation of cell population proliferation
GO:0014069 postsynaptic density
GO:0016324 apical plasma membrane
GO:0017124 SH3 domain binding
GO:0030160 synaptic receptor adaptor activity
GO:0030426 growth cone
GO:0030534 adult behavior
GO:0031526 brush border membrane
GO:0035176 social behavior
GO:0035255 ionotropic glutamate receptor binding
GO:0035331 negative regulation of hippo signaling
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0048854 brain morphogenesis
GO:0051124 synaptic assembly at neuromuscular junction
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060170 ciliary membrane
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0060997 dendritic spine morphogenesis
GO:0060999 positive regulation of dendritic spine development
GO:0071625 vocalization behavior
GO:0097107 postsynaptic density assembly
GO:2000311 regulation of AMPA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
SHANK2PLCG1IntAct17474147 details
SHANK2CRKIntAct17474147 details
SHANK2SRCIntAct17474147 details
SHANK2GRB2IntAct17474147 details
SHANK2NCK1IntAct17474147 details
SHANK2PIK3R1IntAct17474147 details
SHANK2PPP3CABioGRID, IntAct32296183 details
SHANK2ARHGAP12BioGRID, IntAct32296183 details
SHANK2HOMER1BioGRID, IntAct32296183 details
SHANK2BAIAP2BioGRID, HPRD, IntAct12504591 32296183 details
SHANK2RIPOR3BioGRID, IntAct32296183 details
SHANK2BAIAP2L1DIP21098279 details
SHANK2CTTNBioGRID, HPRD9742101 details
SHANK2DNM2BioGRID, HPRD11583995 details
SHANK2ARHGEF7BioGRID, HPRD12626503 32661924 details
SHANK2DLGAP1BioGRID, HPRD10527873 10844022 details
SHANK2DLG4BioGRID, HPRD10527873 10844022 details
SHANK2DLGAP3BioGRID10527873 details
SHANK2DLGAP4BioGRID10527873 details
SHANK2SHARPINBioGRID23897824 details
SHANK2ADGRL2HPRD10964907 details
SHANK2ADGRL1HPRD10958799 10964907 details
SHANK2SSTR2HPRD10373412 11087996 details
SHANK2SLC9A3HPRD16293618 details
SHANK2PDE4DIntAct17244609 details
SHANK2DYNLL2BioGRID10844022 details
SHANK2DYNLL1BioGRID10844022 details
SHANK2MYO5ABioGRID10844022 details
SHANK2RETBioGRID28794017 details
SHANK2GRB10BioGRID28794017 details
SHANK2MYCIntAct21150319 details
SHANK2NLKBioGRID, IntAct23602568 details
SHANK2ESR1BioGRID, IntAct31527615 details
SHANK2XPO1BioGRID26673895 details
SHANK2CDH1BioGRID25468996 details
SHANK2EGFRBioGRID28065597 details
SHANK2ESR2BioGRID29509190 details
SHANK2TRIM25BioGRID29117863 details
SHANK2HNRNPLBioGRID28611215 details