Entity Details

Primary name USP21
Entity type gene
Source Source Link

Details

PrimaryID27005
RefseqGene
SymbolUSP21
Nameubiquitin specific peptidase 21
Chromosome1
Location1q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsUBP21_HUMAN

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008234 cysteine-type peptidase activity
GO:0016578 histone deubiquitination
GO:0016579 protein deubiquitination
GO:0019784 NEDD8-specific protease activity
GO:0031175 neuron projection development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046872 metal ion binding

Diseases

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Interactions

148 interactions

InteractorPartnerSourcesPublicationsLink
USP21EXOSC10BioGRID, HPRD, IntAct15231747 details
USP21USP20BioGRID, IntAct19615732 22626734 details
USP21UCHL1BioGRID, IntAct19615732 22626734 32814053 details
USP21KRT40BioGRID, IntAct25416956 details
USP21EFEMP2BioGRID, IntAct32296183 details
USP21HOXC10BioGRID, IntAct32296183 details
USP21CPSF6BioGRID, IntAct32296183 details
USP21ADAMTSL4BioGRID, IntAct32296183 details
USP21KCTD9BioGRID, IntAct32296183 details
USP21UBCBioGRID20622874 21399617 22195557 22298430 22626734 23287719 25527291 27436899 27501351 28536428 28943312 details
USP21UBE2SBioGRID20622874 details
USP21TRAF6BioGRID20622874 details
USP21ISG15BioGRID21399617 details
USP21TRIM63BioGRID22626734 details
USP21TRIM54BioGRID22626734 details
USP21USP51BioGRID22626734 details
USP21ATXN3BioGRID22626734 details
USP21USP7BioGRID22626734 details
USP21STAMBPBioGRID22626734 details
USP21OTUB1BioGRID22626734 details
USP21JOSD1BioGRID22626734 details
USP21UCHL3BioGRID22626734 details
USP21USP8BioGRID22626734 details
USP21USP21BioGRID22626734 details
USP21OTUB2BioGRID22626734 details
USP21USP33BioGRID22626734 details
USP21USP15BioGRID22626734 details
USP21USP28BioGRID22626734 details
USP21ESPL1BioGRID22626734 details
USP21SENP8BioGRID22626734 details
USP21USP14BioGRID22626734 details
USP21USP2BioGRID22626734 details
USP21BAP1BioGRID22626734 details
USP21YOD1BioGRID22626734 details
USP21SENP3BioGRID22626734 details
USP21USP4BioGRID22626734 details
USP21CBLCBioGRID23105109 details
USP21CBLBioGRID23105109 details
USP21TRIM23BioGRID23105109 details
USP21RNF144ABioGRID23105109 details
USP21LRSAM1BioGRID23105109 details
USP21RBCK1BioGRID23105109 details
USP21TRIM8BioGRID23105109 details
USP21PCGF6BioGRID23105109 details
USP21TRIM5BioGRID23105109 details
USP21RNF185BioGRID23105109 details
USP21TRIM9BioGRID23105109 details
USP21DTX3BioGRID23105109 details
USP21H2AC18BioGRID21179169 details
USP21AURKABioGRID26446837 details
USP21NANOGBioGRID27886188 27956178 29263902 30809310 details
USP21MAPK3BioGRID27886188 details
USP21ZNF350BioGRID27621083 details
USP21KCTD6BioGRID27621083 details
USP21WDR47BioGRID27621083 details
USP21SYNE1BioGRID27621083 details
USP21MPP1BioGRID27621083 details
USP21SLF1BioGRID27621083 details
USP21TP53BioGRID27561390 details
USP21BRCA2BioGRID28743957 details
USP21FOXM1BioGRID30865895 details
USP21UBE2D1BioGRID31951392 details
USP21CDC34BioGRID25764917 details
USP21MARK3BioGRID, IntAct19615732 22298430 details
USP21BEND3BioGRID, IntAct19615732 26100909 details
USP21MARK1BioGRID, IntAct19615732 22298430 details
USP21MARK2BioGRID, IntAct19615732 22298430 details
USP21DCLK1BioGRID, IntAct27173435 unassigned1312 details
USP21SIPA1L1BioGRID, IntAct27173435 unassigned1312 details
USP21KIF1CBioGRID, IntAct27173435 unassigned1312 details
USP21NADKBioGRID, IntAct27173435 unassigned1312 details
USP21AFDNBioGRID, IntAct27173435 unassigned1312 details
USP21HDAC4BioGRID, IntAct27173435 unassigned1312 details
USP21MELKBioGRID, IntAct27173435 unassigned1312 details
USP21TBC1D25BioGRID, IntAct27173435 unassigned1312 details
USP21PLEKHA7BioGRID, IntAct27173435 unassigned1312 details
USP21SYDE1BioGRID, IntAct27173435 unassigned1312 details
USP21FAM110BBioGRID, IntAct27173435 unassigned1312 details
USP21SRSF12BioGRID, IntAct27173435 unassigned1312 details
USP21MAGI1BioGRID, IntAct27173435 unassigned1312 details
USP21TESK2BioGRID, IntAct27173435 unassigned1312 details
USP21FAM110ABioGRID, IntAct27173435 unassigned1312 details
USP21KIF13BBioGRID, IntAct27173435 unassigned1312 details
USP21SH3BP4BioGRID, IntAct27173435 unassigned1312 details
USP21LRFN1BioGRID, IntAct27173435 unassigned1312 details
USP21LIMA1BioGRID, IntAct27173435 unassigned1312 details
USP21CDK16BioGRID, IntAct27173435 unassigned1312 details
USP21TIAM1BioGRID, IntAct27173435 unassigned1312 details
USP21NF1BioGRID, IntAct27173435 unassigned1312 details
USP21SRGAP2BioGRID, IntAct27173435 unassigned1312 details
USP21EIF4E2BioGRID, IntAct27173435 unassigned1312 details
USP21MAST3BioGRID, IntAct27173435 unassigned1312 details
USP21RASAL2BioGRID, IntAct27173435 unassigned1312 details
USP21KCTD3BioGRID, IntAct27173435 unassigned1312 details
USP21PPM1HBioGRID, IntAct27173435 unassigned1312 details
USP21GAB2BioGRID, IntAct27173435 unassigned1312 details
USP21FAM53CBioGRID, IntAct27173435 unassigned1312 details
USP21RTKNBioGRID, IntAct27173435 unassigned1312 details
USP21MAPKAP1BioGRID, IntAct27173435 unassigned1312 details
USP21RAB3IPBioGRID, IntAct27173435 unassigned1312 details
USP21DEPDC1BBioGRID, IntAct27173435 unassigned1312 details
USP21DENND1ABioGRID, IntAct27173435 unassigned1312 details
USP21KSR1BioGRID, IntAct27173435 unassigned1312 details
USP21PHLDB2BioGRID, IntAct27173435 unassigned1312 details
USP21ANKRD34ABioGRID, IntAct27173435 unassigned1312 details
USP21DENND4CBioGRID, IntAct27173435 unassigned1312 details
USP21SH3PXD2ABioGRID, IntAct27173435 unassigned1312 details
USP21MAP3K21BioGRID, IntAct27173435 unassigned1312 details
USP21ZNF638BioGRID, IntAct27173435 unassigned1312 details
USP21CDC25BBioGRID, IntAct27173435 unassigned1312 details
USP21ZBTB21BioGRID, IntAct27173435 unassigned1312 details
USP21AGAP1BioGRID, IntAct27173435 unassigned1312 details
USP21CBY1BioGRID, IntAct27173435 unassigned1312 details
USP21RIPK1BioGRID19910467 details
USP21XPO1BioGRID21888622 details
USP21MAP4BioGRID22298430 details
USP21ARHGEF2BioGRID22298430 details
USP21CKAP5BioGRID22298430 details
USP21GATA3BioGRID23395819 details
USP21DDX58BioGRID24493797 details
USP21IFIH1BioGRID24493797 details
USP21DHX58BioGRID24493797 details
USP21IL33BioGRID25197364 details
USP21BHLHE40BioGRID25202122 details
USP21BAZ2ABioGRID26100909 details
USP21CUL3BioGRID27621083 details
USP21GLI1BioGRID27621083 details
USP21KCTD11BioGRID27621083 details
USP21GLI2BioGRID27621083 details
USP21RAD51BioGRID28743957 details
USP21CTNNB1BioGRID30323974 details
USP21GSCBioGRID31253698 details
USP21TCF7BioGRID31488580 details
USP21SNAI1BioGRID31911859 details
USP21PPP6R3BioGRID, IntAct19615732 details
USP21UPF3BBioGRID, IntAct19615732 details
USP21RBM8ABioGRID, IntAct19615732 details
USP21ANKRD28BioGRID, IntAct19615732 details
USP21PRKCIBioGRID, IntAct19615732 details
USP21RBM45BioGRID, IntAct19615732 details
USP21PPIBBioGRID, IntAct19615732 details
USP21FUCA1BioGRID, IntAct19615732 details
USP21USP48BioGRID, IntAct19615732 details
USP21UTRNBioGRID, IntAct19615732 details
USP21YWHAGIntAct28514442 details
USP21YWHAHIntAct28514442 details
USP21MARK4BioGRID19615732 details
USP21HECW2BioGRID24163370 details