Entity Details

Primary name CBX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14781
EntryNameCBX2_HUMAN
FullNameChromobox protein homolog 2
TaxID9606
Evidenceevidence at protein level
Length532
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesCBX2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006325 chromatin organization
GO:0030154 cell differentiation
GO:0031519 PcG protein complex
GO:0035064 methylated histone binding
GO:0035102 PRC1 complex
GO:0045137 development of primary sexual characteristics

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR023779 Chromo domain, conserved siteSiteConserved site
IPR023780 Chromo domainDomainDomain
IPR033773 CBX family C-terminal motifSiteConserved site
IPR042796 Chromobox protein homolog 2FamilyFamily

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
CBX2_HUMANKR412_HUMANBioGRID, HPRD, IntAct16189514 details
CBX2_HUMANMDFI_HUMANBioGRID, HPRD, IntAct16189514 19060904 32296183 details
CBX2_HUMANPCGF2_HUMANBioGRID, IntAct, MINT, UniProt19636380 20601937 22325352 24981860 27705803 28514442 31093962 details
CBX2_HUMANPHC2_HUMANBioGRID, IntAct, UniProt21282530 22325352 24981860 27705803 31093962 details
CBX2_HUMANRING2_HUMANBioGRID, DIP, IntAct, MINT, UniProt18927235 21282530 22325352 24457600 24981860 26496610 27705803 31093962 details
CBX2_HUMANRING1_HUMANBioGRID, IntAct, MINT10369680 22325352 24981860 27705803 details
CBX2_HUMANKRA23_HUMANBioGRID, IntAct25416956 details
CBX2_HUMANRBY1A_HUMANBioGRID, IntAct25416956 details
CBX2_HUMANKR107_HUMANBioGRID, IntAct25416956 details
CBX2_HUMANKR109_HUMANBioGRID, IntAct25416956 details
CBX2_HUMANRBY1F_HUMANBioGRID, IntAct25416956 32296183 details
CBX2_HUMANDHX57_HUMANBioGRID, IntAct25416956 32296183 details
CBX2_HUMANKR122_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANRBPS2_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANKRA44_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANKR123_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANBOLL_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
CBX2_HUMANH32_HUMANDIP18927235 details
CBX2_HUMANH31_HUMANBioGRID, DIP, MINT18927235 25281560 34079125 details
CBX2_HUMANH33_HUMANDIP18927235 details
CBX2_HUMANTRI63_HUMANBioGRID, IntAct31391242 details
CBX2_HUMANTRI55_HUMANBioGRID, IntAct31391242 details
CBX2_HUMANTF2B_HUMANIntAct32814053 details
CBX2_HUMANSYYC_HUMANIntAct32814053 details
CBX2_HUMANTF3C3_HUMANIntAct32814053 details
CBX2_HUMANSPRE1_HUMANIntAct32814053 details
CBX2_HUMANTADBP_HUMANIntAct32814053 details
CBX2_HUMANRYBP_HUMANBioGRID, HPRD10369680 24981860 details
CBX2_HUMANH31T_HUMANBioGRID20850016 21047797 details
CBX2_HUMANKRA24_HUMANBioGRID25416956 details
CBX2_HUMANKR101_HUMANBioGRID25416956 details
CBX2_HUMANKR103_HUMANBioGRID25416956 details
CBX2_HUMANMEOX2_HUMANBioGRID32296183 details
CBX2_HUMANUBP7_HUMANMINT20601937 details
CBX2_HUMANUBP11_HUMANMINT20601937 details
CBX2_HUMANBMI1_HUMANBioGRID, IntAct, MINT, UniProt19636380 20601937 21282530 22325352 24457600 24981860 27705803 details
CBX2_HUMANH2AX_HUMANBioGRID21383063 details
CBX2_HUMANCBX4_HUMANBioGRID21282530 22325352 24981860 details
CBX2_HUMANH2B1B_HUMANBioGRID21282530 details