Entity Details

Primary name PDCD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15116
EntryNamePDCD1_HUMAN
FullNameProgrammed cell death protein 1
TaxID9606
Evidenceevidence at protein level
Length288
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPDCD1

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006959 humoral immune response
GO:0007275 multicellular organism development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0031295 T cell costimulation
GO:0050776 regulation of immune response
GO:0050777 negative regulation of immune response
GO:0070234 positive regulation of T cell apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042379 Programmed cell death protein 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB05916 CT-011Drugbankbiotech
DB09035 NivolumabDrugbankbiotech
DB09037 PembrolizumabDrugbankbiotech
DB14707 CemiplimabDrugbankbiotech
DB14776 CamrelizumabDrugbankbiotech
DB14892 SpartalizumabDrugbankbiotech
DB14922 TislelizumabDrugbankbiotech
DB15043 ToripalimabDrugbankbiotech
DB15627 DostarlimabDrugbankbiotech
DB15765 SintilimabDrugbankbiotech
DB15766 RetifanlimabDrugbankbiotech
DB15767 AMP-224Drugbankbiotech
DB15768 MEDI0680Drugbankbiotech