Entity Details

Primary name IRF5
Entity type gene
Source Source Link

Details

PrimaryID3663
RefseqGeneNG_012306
SymbolIRF5
Nameinterferon regulatory factor 5
Chromosome7
Location7q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-10-16
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIRF5_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002376 immune system process
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006954 inflammatory response
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0032481 positive regulation of type I interferon production
GO:0032494 response to peptidoglycan
GO:0032495 response to muramyl dipeptide
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032735 positive regulation of interleukin-12 production
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
IRF5SGTABioGRID, IntAct21988832 details
IRF5MAVSBioGRID, IntAct21903422 details
IRF5CREBBPBioGRID, DIP18836453 20935208 details
IRF5IRF5BioGRID, DIP, HPRD12138184 18836453 19786094 details
IRF5TRIM15BioGRID, IntAct20211142 details
IRF5IRF3BioGRID, HPRD11303025 12138184 details
IRF5HDAC1BioGRID20935208 details
IRF5SIN3ABioGRID20935208 details
IRF5NCOR2BioGRID20935208 details
IRF5EP300BioGRID20935208 details
IRF5ALPIBioGRID19786094 details
IRF5MYD88BioGRID, HPRD15665823 details
IRF5TRIM21BioGRID25084355 details
IRF5COPS3BioGRID29339435 details
IRF5GPS1BioGRID, IntAct21903422 29339435 details
IRF5RELAIntAct20237317 details
IRF5NCOR1BioGRID20935208 details
IRF5KAT2BBioGRID20935208 details
IRF5CHUKBioGRID19786094 details
IRF5TRAF6BioGRID, HPRD15665823 32494619 details
IRF5BIRC3BioGRID25565375 details
IRF5PELI1BioGRID28746869 details
IRF5COPS7ABioGRID29339435 details
IRF5COPS4BioGRID29339435 details
IRF5COPS8BioGRID29339435 details
IRF5COPS6BioGRID29339435 details
IRF5COPS2BioGRID29339435 details
IRF5COPS5BioGRID29339435 details
IRF5OGTBioGRID32494619 details
IRF5OGABioGRID32494619 details
IRF5XPO1HPRD15556946 details
IRF5IKBKEHPRD15556946 15695821 details
IRF5TBK1HPRD15556946 15695821 details
IRF5RGS3BioGRID, IntAct21903422 details
IRF5GTPBP1BioGRID, IntAct21903422 details
IRF5CEP152BioGRID, IntAct21903422 26638075 details
IRF5GRB2BioGRID, IntAct21903422 details
IRF5PPM1GBioGRID, IntAct21903422 details
IRF5HIVEP1BioGRID, IntAct21903422 details
IRF5GTPBP2BioGRID, IntAct21903422 details
IRF5IRF6BioGRID, IntAct21903422 details
IRF5PPIBBioGRID, IntAct30021884 details
IRF5SLC15A4UniProt32433612 details
IRF5CCL21IntAct33179750 details