Entity Details

Primary name ASAH1
Entity type gene
Source Source Link

Details

PrimaryID427
RefseqGeneNG_008985
SymbolASAH1
NameN-acylsphingosine amidohydrolase 1
Chromosome8
Location8p22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-11
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsASAH1_HUMAN

GO terms

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GOName
GO:0003714 transcription corepressor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0006631 fatty acid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0016922 nuclear receptor binding
GO:0017040 N-acylsphingosine amidohydrolase activity
GO:0017064 fatty acid amide hydrolase activity
GO:0030216 keratinocyte differentiation
GO:0043202 lysosomal lumen
GO:0043312 neutrophil degranulation
GO:0046512 sphingosine biosynthetic process
GO:0046513 ceramide biosynthetic process
GO:0046514 ceramide catabolic process
GO:0050810 regulation of steroid biosynthetic process
GO:0062098 regulation of programmed necrotic cell death
GO:0070062 extracellular exosome
GO:0071356 cellular response to tumor necrosis factor
GO:0102121 ceramidase activity
GO:1903507 negative regulation of nucleic acid-templated transcription
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
ASAH1SETDB1BioGRID, HPRD, IntAct16169070 details
ASAH1TSC22D1BioGRID, HPRD, IntAct16169070 details
ASAH1CAMK1DBioGRID, IntAct21988832 details
ASAH1SRPK1BioGRID, IntAct23602568 details
ASAH1HSPB2bhf-ucl, BioGRID26465331 details
ASAH1BACE2IntAct32814053 details
ASAH1SMPD1HPRD12815059 details
ASAH1A2MMINT17174955 details
ASAH1FTH1BioGRID, IntAct28514442 details
ASAH1TBC1D22BBioGRID, IntAct28514442 details
ASAH1PNKDBioGRID, IntAct26186194 28514442 details
ASAH1TRMT2ABioGRID, IntAct28514442 details
ASAH1AAGABBioGRID, IntAct26186194 28514442 details
ASAH1SLCO6A1BioGRID, IntAct28514442 details
ASAH1CYP1A2BioGRID, IntAct28514442 details
ASAH1HSF2BioGRID, IntAct26186194 28514442 details
ASAH1ZIC1BioGRID, IntAct28514442 details
ASAH1ZNF556BioGRID, IntAct28514442 details
ASAH1AIREBioGRID, IntAct28514442 details
ASAH1RNF6BioGRID, IntAct28514442 details
ASAH1GLT1D1BioGRID, IntAct28514442 details
ASAH1LYPD1BioGRID, IntAct28514442 details
ASAH1NSG2BioGRID, IntAct28514442 details
ASAH1AAMPBioGRID, IntAct26186194 28514442 details
ASAH1HTATIP2BioGRID, IntAct28514442 details
ASAH1GSG1BioGRID, IntAct26186194 28514442 details
ASAH1NONOBioGRID, IntAct28514442 details
ASAH1PSMA3BioGRID22079093 details
ASAH1FBXO6BioGRID22268729 32409323 details
ASAH1NEFHBioGRID26186194 details
ASAH1CAMK2BBioGRID26186194 details
ASAH1HERC2BioGRID25476789 details
ASAH1ZNF684BioGRID28514442 details
ASAH1NCDNBioGRID28561026 details
ASAH1ESR2BioGRID29509190 details
ASAH1CD274BioGRID32941674 details
ASAH1APEX1BioGRID28986522 details