Entity Details

Primary name NDF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15784
EntryNameNDF2_HUMAN
FullNameNeurogenic differentiation factor 2
TaxID9606
Evidenceevidence at transcript level
Length382
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNEUROD2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001662 behavioral fear response
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008306 associative learning
GO:0016567 protein ubiquitination
GO:0021695 cerebellar cortex development
GO:0030182 neuron differentiation
GO:0031915 positive regulation of synaptic plasticity
GO:0045666 positive regulation of neuron differentiation
GO:0046982 protein heterodimerization activity
GO:0048666 neuron development
GO:0050850 positive regulation of calcium-mediated signaling
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070888 E-box binding
GO:0071257 cellular response to electrical stimulus
GO:0071277 cellular response to calcium ion
GO:0090129 positive regulation of synapse maturation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000297 negative regulation of synapse maturation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR016637 Neurogenic differentiation factor NeuroDFamilyFamily
IPR022575 Neurogenic differentiation factor, domain of unknown functionDomainDomain
IPR032649 Neurogenic differentiation factor 2FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NDF2_HUMANKITH_HUMANBioGRID, MINT21900206 details
NDF2_HUMANPKN1_HUMANBioGRID, HPRD10640683 details
NDF2_HUMANFMR1_HUMANIntAct31413325 details