Entity Details

Primary name MVK
Entity type gene
Source Source Link

Details

PrimaryID4598
RefseqGeneNG_007702
SymbolMVK
Namemevalonate kinase
Chromosome12
Location12q24.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-01-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsKIME_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004496 mevalonate kinase activity
GO:0005524 ATP binding
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0006695 cholesterol biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0050728 negative regulation of inflammatory response

Diseases

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Interactions

19 interactions

InteractorPartnerSourcesPublicationsLink
MVKMVKBioGRID, HPRD, IntAct16189514 25416956 25502805 26871637 31515488 32296183 details
MVKEWSR1BioGRID, HPRD, IntAct16189514 31515488 details
MVKTERF1bhf-ucl, BioGRID21044950 details
MVKPOT1bhf-ucl, BioGRID21044950 details
MVKRNF141BioGRID, IntAct32296183 details
MVKKHDRBS2BioGRID, IntAct28514442 details
MVKKLHL10BioGRID, IntAct28514442 details
MVKGGT5BioGRID, IntAct28514442 details
MVKSPACA4BioGRID, IntAct26186194 28514442 details
MVKTACC3BioGRID, IntAct28514442 details
MVKCCDC91BioGRID, IntAct26186194 28514442 details
MVKMAT1ABioGRID22939629 26344197 details
MVKGSSBioGRID22863883 details
MVKPPP1CBBioGRID22863883 details
MVKENO1BioGRID22658674 details
MVKMOV10BioGRID22658674 details
MVKNXF1BioGRID22658674 details
MVKAPEX1BioGRID28986522 details
MVKDDX58BioGRID32513696 details