Entity Details

Primary name OTX2
Entity type gene
Source Source Link

Details

PrimaryID5015
RefseqGeneNG_008204
SymbolOTX2
Nameorthodenticle homeobox 2
Chromosome14
Location14q22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-07-28
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsOTX2_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007411 axon guidance
GO:0008190 eukaryotic initiation factor 4E binding
GO:0008589 regulation of smoothened signaling pathway
GO:0030426 growth cone
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0032991 protein-containing complex
GO:0040019 positive regulation of embryonic development
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0065003 protein-containing complex assembly
GO:0071542 dopaminergic neuron differentiation
GO:0090009 primitive streak formation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000543 positive regulation of gastrulation

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
OTX2ATXN1BioGRID, HPRD, IntAct16713569 23275563 32814053 details
OTX2CDK4BioGRID, IntAct22094256 details
OTX2ZDHHC17BioGRID, IntAct24705354 details
OTX2M1APBioGRID, IntAct32296183 details
OTX2ATP6V1G3BioGRID, IntAct32296183 details
OTX2GPR45BioGRID, IntAct32296183 details
OTX2HSD3B7BioGRID, IntAct32296183 details
OTX2ZNHIT1BioGRID, IntAct32296183 details
OTX2JPT1BioGRID, IntAct32296183 details
OTX2TBCELBioGRID, IntAct32296183 details
OTX2HIKESHIBioGRID, IntAct32296183 details
OTX2HNF1BBioGRID, IntAct32296183 details
OTX2IQGAP1BioGRID, IntAct32296183 details
OTX2RTCABioGRID, IntAct32296183 details
OTX2RBM47BioGRID, IntAct32296183 details
OTX2NAA50BioGRID, IntAct32296183 details
OTX2AURKCBioGRID, IntAct32296183 details
OTX2OR1L3BioGRID, IntAct32296183 details
OTX2CDK3BioGRID, IntAct32296183 details
OTX2ZNF765BioGRID, IntAct32296183 details
OTX2TENT5BBioGRID, IntAct32296183 details
OTX2HOMER3BioGRID, IntAct32296183 details
OTX2B4GALNT2BioGRID, IntAct32296183 details
OTX2KLF3BioGRID, IntAct32296183 details
OTX2SNRPABioGRID, IntAct32296183 details
OTX2TNPO2BioGRID, IntAct32296183 details
OTX2BNIP2BioGRID, IntAct32296183 details
OTX2TRMT10BBioGRID, IntAct32296183 details
OTX2GUCA1BBioGRID, IntAct32296183 details
OTX2ASIC4BioGRID, IntAct32296183 details
OTX2OR6C1BioGRID, IntAct32296183 details
OTX2ZC3H10BioGRID, IntAct32296183 details
OTX2RPS26BioGRID, IntAct32296183 details
OTX2RNASE11BioGRID, IntAct32296183 details
OTX2TMEM11BioGRID, IntAct32296183 details
OTX2DYNC1H1IntAct32814053 details
OTX2PAK1IntAct32814053 details
OTX2FOXA2BioGRID, HPRD10623575 12642491 details
OTX2OTX2BioGRID10623575 details
OTX2LHX1BioGRID10623575 details
OTX2APPBioGRID21244100 21832049 details
OTX2SMARCB1BioGRID27229929 details
OTX2POLDIP3BioGRID32296183 details
OTX2TLE4HPRD15105370 details
OTX2MITFHPRD12663655 details
OTX2DMBX1HPRD15890343 details
OTX2BCORBioGRID26687479 details
OTX2NANOGBioGRID26687479 details
OTX2POU5F1BioGRID26687479 details