Entity Details

Primary name PCK1
Entity type gene
Source Source Link

Details

PrimaryID5105
RefseqGeneNG_008205
SymbolPCK1
Namephosphoenolpyruvate carboxykinase 1
Chromosome20
Location20q13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPCKGC_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006006 glucose metabolic process
GO:0006094 gluconeogenesis
GO:0006107 oxaloacetate metabolic process
GO:0007568 aging
GO:0014823 response to activity
GO:0018105 peptidyl-serine phosphorylation
GO:0019003 GDP binding
GO:0019543 propionate catabolic process
GO:0030145 manganese ion binding
GO:0030522 intracellular receptor signaling pathway
GO:0031406 carboxylic acid binding
GO:0032496 response to lipopolysaccharide
GO:0032868 response to insulin
GO:0032869 cellular response to insulin stimulus
GO:0033993 response to lipid
GO:0042593 glucose homeostasis
GO:0042594 response to starvation
GO:0043382 positive regulation of memory T cell differentiation
GO:0046327 glycerol biosynthetic process from pyruvate
GO:0046890 regulation of lipid biosynthetic process
GO:0051365 cellular response to potassium ion starvation
GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
GO:0070062 extracellular exosome
GO:0070365 hepatocyte differentiation
GO:0070741 response to interleukin-6
GO:0071300 cellular response to retinoic acid
GO:0071320 cellular response to cAMP
GO:0071332 cellular response to fructose stimulus
GO:0071333 cellular response to glucose stimulus
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071377 cellular response to glucagon stimulus
GO:0071456 cellular response to hypoxia
GO:0071549 cellular response to dexamethasone stimulus
GO:0106264 protein serine kinase activity (using GTP as donor)
GO:1904640 response to methionine

Diseases

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Interactions

81 interactions

InteractorPartnerSourcesPublicationsLink
PCK1C1RBioGRID, IntAct21988832 details
PCK1IKBKGBioGRID20098747 details
PCK1UBR5BioGRID21726808 30552140 details
PCK1APPBioGRID21832049 details
PCK1FBXO25BioGRID23940030 details
PCK1INSIG1BioGRID32322062 details
PCK1INSIG2BioGRID32322062 details
PCK1AKT1BioGRID32322062 details
PCK1BAG6BioGRID21726808 details
PCK1SIRT2BioGRID21726808 details
PCK1EP300BioGRID21726808 28240261 details
PCK1UBE2IBioGRID28240261 details
PCK1NR4A1BioGRID28240261 details
PCK1CUL5BioGRID, IntAct21145461 details
PCK1NDUFA11BioGRID, MINT24344204 details
PCK1PCK2BioGRID, IntAct28514442 details
PCK1PSMC4BioGRID21726808 details
PCK1HLA-CBioGRID21726808 details
PCK1YWHAQBioGRID21726808 details
PCK1ABCB7BioGRID21726808 details
PCK1ACTBBioGRID21726808 details
PCK1ATP2A1BioGRID21726808 details
PCK1BSGBioGRID21726808 details
PCK1CALM1BioGRID21726808 details
PCK1CALM2BioGRID21726808 details
PCK1CALM3BioGRID21726808 details
PCK1HSPD1BioGRID21726808 details
PCK1CPT1ABioGRID21726808 details
PCK1DNAJA1BioGRID21726808 details
PCK1GNAI1BioGRID21726808 details
PCK1HSPA1LBioGRID21726808 details
PCK1LDHABioGRID21726808 details
PCK1MAGED2BioGRID21726808 details
PCK1PSMC1BioGRID21726808 details
PCK1PSMC2BioGRID21726808 details
PCK1PSMC5BioGRID21726808 details
PCK1PSMA2BioGRID21726808 details
PCK1PSMA5BioGRID21726808 details
PCK1PSMB1BioGRID21726808 details
PCK1PSMB4BioGRID21726808 details
PCK1PSMD12BioGRID21726808 details
PCK1RPL4BioGRID21726808 details
PCK1RPL10LBioGRID21726808 details
PCK1RPL14BioGRID21726808 details
PCK1RPL23BioGRID21726808 details
PCK1RPLP0BioGRID21726808 details
PCK1RPS3ABioGRID21726808 details
PCK1RPS6BioGRID21726808 details
PCK1RPS15ABioGRID21726808 details
PCK1SKP1BioGRID21726808 details
PCK1TCP1BioGRID21726808 details
PCK1CCT2BioGRID21726808 details
PCK1CCT4BioGRID21726808 details
PCK1CCT5BioGRID21726808 details
PCK1C1QBPBioGRID21726808 details
PCK1TSC22D3BioGRID21726808 details
PCK1USP11BioGRID21726808 details
PCK1ELOCBioGRID21726808 details
PCK1HLA-BBioGRID21726808 details
PCK1GNA12BioGRID21726808 details
PCK1GNASBioGRID21726808 details
PCK1GPHNBioGRID21726808 details
PCK1DDX21BioGRID21726808 details
PCK1MAGED1BioGRID21726808 details
PCK1DDX3XBioGRID21726808 details
PCK1MYLK2BioGRID21726808 details
PCK1NUP62BioGRID21726808 details
PCK1PSMB7BioGRID21726808 details
PCK1GIGYF2BioGRID21726808 details
PCK1SQSTM1BioGRID21726808 details
PCK1FASNBioGRID21726808 details
PCK1PSMD2BioGRID21726808 details
PCK1IRS4BioGRID21726808 details
PCK1SRPRBBioGRID21726808 details
PCK1LPCAT1BioGRID21726808 details
PCK1FAF2BioGRID21726808 details
PCK1PSMD6BioGRID21726808 details
PCK1RPS3BioGRID21726808 details
PCK1UBCBioGRID21726808 details
PCK1PSMD14BioGRID21726808 details
PCK1ZNF746IntAct21376232 details