Entity Details

Primary name GRIK5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16478
EntryNameGRIK5_HUMAN
FullNameGlutamate receptor ionotropic, kainate 5
TaxID9606
Evidenceevidence at transcript level
Length980
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesGRIK5

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006621 protein retention in ER lumen
GO:0008066 glutamate receptor activity
GO:0015276 ligand-gated ion channel activity
GO:0015277 kainate selective glutamate receptor activity
GO:0017124 SH3 domain binding
GO:0030165 PDZ domain binding
GO:0030425 dendrite
GO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane
GO:0032983 kainate selective glutamate receptor complex
GO:0035249 synaptic transmission, glutamatergic
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0043113 receptor clustering
GO:0043195 terminal bouton
GO:0043204 perikaryon
GO:0043525 positive regulation of neuron apoptotic process
GO:0045211 postsynaptic membrane
GO:0050804 modulation of chemical synaptic transmission
GO:0051649 establishment of localization in cell
GO:0060079 excitatory postsynaptic potential
GO:0071333 cellular response to glucose stimulus
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:0099061 integral component of postsynaptic density membrane
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule