Entity Details

Primary name TLR9
Entity type gene
Source Source Link

Details

PrimaryID54106
RefseqGeneNG_033933
SymbolTLR9
Nametoll like receptor 9
Chromosome3
Location3p21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-02
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsTLR9_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002224 toll-like receptor signaling pathway
GO:0002237 response to molecule of bacterial origin
GO:0002639 positive regulation of immunoglobulin production
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0004888 transmembrane signaling receptor activity
GO:0005149 interleukin-1 receptor binding
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007252 I-kappaB phosphorylation
GO:0010008 endosome membrane
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0030277 maintenance of gastrointestinal epithelium
GO:0030890 positive regulation of B cell proliferation
GO:0032009 early phagosome
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032640 tumor necrosis factor production
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032722 positive regulation of chemokine production
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032729 positive regulation of interferon-gamma production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032741 positive regulation of interleukin-18 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0034123 positive regulation of toll-like receptor signaling pathway
GO:0034162 toll-like receptor 9 signaling pathway
GO:0034163 regulation of toll-like receptor 9 signaling pathway
GO:0035197 siRNA binding
GO:0036019 endolysosome
GO:0036020 endolysosome membrane
GO:0038187 pattern recognition receptor activity
GO:0042742 defense response to bacterium
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410 positive regulation of MAPK cascade
GO:0043507 positive regulation of JUN kinase activity
GO:0045087 innate immune response
GO:0045322 unmethylated CpG binding
GO:0045577 regulation of B cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0050729 positive regulation of inflammatory response
GO:0050829 defense response to Gram-negative bacterium
GO:0050871 positive regulation of B cell activation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1901895 negative regulation of ATPase-coupled calcium transmembrane transporter activity

Diseases

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Interactions

60 interactions

InteractorPartnerSourcesPublicationsLink
TLR9NCK1IntAct17474147 details
TLR9SIGLEC5IntAct25187624 details
TLR9SIGLEC6IntAct25187624 details
TLR9SIGLEC9IntAct25187624 details
TLR9TLR9IntAct23155421 details
TLR9RNF216BioGRID, HPRD15107846 details
TLR9MYD88BioGRID15107846 21911421 details
TLR9BTKBioGRID, HPRD12724322 details
TLR9TLR8IntAct17040905 details
TLR9STUB1BioGRID21911421 details
TLR9IRAK1BioGRID21911421 details
TLR9TRIM69BioGRID21911421 details
TLR9TBK1BioGRID21911421 details
TLR9TRAF6BioGRID21911421 details
TLR9HSPA8BioGRID21911421 details
TLR9SRCBioGRID21911421 details
TLR9PRKCZBioGRID21911421 details
TLR9SYKBioGRID23962979 details
TLR9TNFAIP3BioGRID30277474 details
TLR9SIGIRRHPRD12925853 details
TLR9TLR1HPRD12600829 details
TLR9HRASHPRD12867418 details
TLR9MAPK8IP3HPRD12941697 details
TLR9STK11IPBioGRID, IntAct21903422 details
TLR9TOLLIPBioGRID, IntAct21903422 details
TLR9PALD1BioGRID, IntAct21903422 details
TLR9CLGNBioGRID, IntAct21903422 details
TLR9UNC93B1BioGRID, IntAct21903422 details
TLR9UGGT1BioGRID, IntAct21903422 details
TLR9TRAF3BioGRID, IntAct21903422 details
TLR9RBMXBioGRID, IntAct30021884 details
TLR9GSK3ABioGRID, UniProt30824926 details
TLR9GSK3BBioGRID, UniProt30824926 details
TLR9STYXBioGRID27432908 details
TLR9HSPA6BioGRID30277474 details
TLR9XRN1BioGRID30277474 details
TLR9MSH3BioGRID30277474 details
TLR9MTDHBioGRID30277474 details
TLR9UNC45ABioGRID30277474 details
TLR9BSCL2BioGRID30277474 details
TLR9PES1BioGRID30277474 details
TLR9KDM1ABioGRID30277474 details
TLR9TPRNBioGRID30277474 details
TLR9TMPOBioGRID30277474 details
TLR9IFI16BioGRID30277474 details
TLR9NFYABioGRID30277474 details
TLR9SMARCA5BioGRID30277474 details
TLR9UPF1BioGRID30277474 details
TLR9PAK2BioGRID30277474 details
TLR9ACTG1BioGRID30277474 details
TLR9GTF2IBioGRID30277474 details
TLR9MYO1CBioGRID30277474 details
TLR9RNH1BioGRID30277474 details
TLR9OGTBioGRID30277474 details
TLR9HSPA4BioGRID30277474 details
TLR9PRKCDBioGRID30277474 details
TLR9INPP5DBioGRID30277474 details
TLR9MCMBPBioGRID30277474 details
TLR9MICAL1BioGRID30277474 details
TLR9PSMD14BioGRID30745168 details