Entity Details

Primary name ERRFI1
Entity type gene
Source Source Link

Details

PrimaryID54206
RefseqGene
SymbolERRFI1
NameERBB receptor feedback inhibitor 1
Chromosome1
Location1p36.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsERRFI_HUMAN

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031267 small GTPase binding
GO:0031953 negative regulation of protein autophosphorylation
GO:0032691 negative regulation of interleukin-1 beta production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032869 cellular response to insulin stimulus
GO:0032966 negative regulation of collagen biosynthetic process
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043589 skin morphogenesis
GO:0045616 regulation of keratinocyte differentiation
GO:0048286 lung alveolus development
GO:0060426 lung vasculature development
GO:0060428 lung epithelium development
GO:0061469 regulation of type B pancreatic cell proliferation
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0071474 cellular hyperosmotic response
GO:0071549 cellular response to dexamethasone stimulus
GO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress

Diseases

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Interactions

101 interactions

InteractorPartnerSourcesPublicationsLink
ERRFI1GRB2BioGRID, IntAct20351267 20936779 21706016 21988832 24189400 28514442 31980649 32296183 details
ERRFI1CHEK1MINT22505024 details
ERRFI1EGFRBioGRID, DIP, HPRD, IntAct11843178 18046415 18271526 18776048 19531499 19815557 23273428 23956138 24189400 24797263 25754235 26280531 28065597 details
ERRFI1ERBB2BioGRID, HPRD, IntAct, MINT11003669 24189400 25640309 details
ERRFI1ATMBioGRID, MINT25640309 details
ERRFI1AURKABioGRID, MINT25640309 details
ERRFI1BAG4BioGRID, MINT25640309 details
ERRFI1BCAR3BioGRID, MINT25640309 details
ERRFI1CASP8BioGRID, MINT25640309 details
ERRFI1FGFR2BioGRID, MINT25640309 details
ERRFI1FGFR4BioGRID, MINT25640309 details
ERRFI1PALB2BioGRID, MINT25640309 details
ERRFI1PPM1DBioGRID, MINT25640309 details
ERRFI1RB1CC1BioGRID, MINT25640309 details
ERRFI1FYNBioGRID, IntAct32296183 details
ERRFI1CDC42BioGRID, HPRD10749885 details
ERRFI1SRCBioGRID26280531 details
ERRFI1ACBD3BioGRID20351267 details
ERRFI1AOX1BioGRID20351267 details
ERRFI1ARRDC5BioGRID20351267 details
ERRFI1RUBCNLBioGRID20351267 details
ERRFI1CRHBPBioGRID20351267 details
ERRFI1DCTN6BioGRID20351267 details
ERRFI1EFEMP1BioGRID20351267 details
ERRFI1CIAO2BBioGRID20351267 details
ERRFI1GAS1BioGRID20351267 details
ERRFI1GNPDA2BioGRID20351267 details
ERRFI1GTF2H2BioGRID20351267 details
ERRFI1HYDINBioGRID20351267 details
ERRFI1IL2RGBioGRID20351267 details
ERRFI1COPS5BioGRID20351267 details
ERRFI1MFSD5BioGRID20351267 details
ERRFI1MMP26BioGRID20351267 details
ERRFI1NEU1BioGRID20351267 details
ERRFI1NPC2BioGRID20351267 details
ERRFI1OSTF1BioGRID20351267 details
ERRFI1PAPSS1BioGRID20351267 details
ERRFI1PCCABioGRID20351267 details
ERRFI1PCNABioGRID20351267 details
ERRFI1PDCD2BioGRID20351267 details
ERRFI1PHYHIPLBioGRID20351267 details
ERRFI1PLEKHA3BioGRID20351267 details
ERRFI1PPIABioGRID20351267 details
ERRFI1PSMA7BioGRID20351267 details
ERRFI1PSMB6BioGRID20351267 details
ERRFI1RAB18BioGRID20351267 details
ERRFI1SH3YL1BioGRID20351267 details
ERRFI1SLC7A13BioGRID20351267 details
ERRFI1STX8BioGRID20351267 details
ERRFI1TC2NBioGRID20351267 details
ERRFI1TIMP4BioGRID20351267 details
ERRFI1TM2D3BioGRID20351267 details
ERRFI1TMEM165BioGRID20351267 details
ERRFI1TMEM59BioGRID20351267 details
ERRFI1WDR61BioGRID20351267 details
ERRFI1YWHABBioGRID20351267 details
ERRFI1ZPBPBioGRID20351267 details
ERRFI1NEDD4BioGRID27557663 details
ERRFI1WEE1BioGRID30067982 details
ERRFI1SFNBioGRID, MINT15778465 details
ERRFI1YWHAZBioGRID, IntAct15778465 24189400 details
ERRFI1PDGFRBBioGRID19815557 details
ERRFI1AXLBioGRID19815557 details
ERRFI1ALKBioGRID19815557 details
ERRFI1LTKBioGRID19815557 details
ERRFI1ACTA2BioGRID24189400 details
ERRFI1ACTBBioGRID24189400 details
ERRFI1ACTC1BioGRID24189400 details
ERRFI1ACTG1BioGRID24189400 details
ERRFI1ACTG2BioGRID24189400 details
ERRFI1ACTA1BioGRID24189400 details
ERRFI1ERRFI1BioGRID24189400 details
ERRFI1GFAPBioGRID24189400 details
ERRFI1HSPA1ABioGRID24189400 details
ERRFI1HSPA8BioGRID24189400 details
ERRFI1POTEEBioGRID24189400 details
ERRFI1POTEFBioGRID24189400 details
ERRFI1TUBA1BBioGRID24189400 details
ERRFI1TUBA1CBioGRID24189400 details
ERRFI1SHC2BioGRID, IntAct24189400 details
ERRFI1YWHAQBioGRID, IntAct24189400 details
ERRFI1CCT3BioGRID, IntAct24189400 details
ERRFI1YWHAEBioGRID, IntAct24189400 31980649 details
ERRFI1SHC1BioGRID, IntAct24189400 details
ERRFI1ANXA2BioGRID, IntAct24189400 details
ERRFI1UBASH3BBioGRID, IntAct24189400 details
ERRFI1MASP1BioGRID, IntAct24189400 details
ERRFI1UBBIntAct24189400 details
ERRFI1UBCIntAct24189400 details
ERRFI1RPS27ABioGRID, IntAct24189400 details
ERRFI1UBA52IntAct24189400 details
ERRFI1ACTBL2BioGRID, IntAct24189400 details
ERRFI1TUBA1ABioGRID, IntAct24189400 details
ERRFI1EGLN3BioGRID, IntAct26972000 details
ERRFI1YWHAGIntAct28514442 details
ERRFI1YWHAHIntAct28514442 details
ERRFI1XPO1BioGRID26673895 details
ERRFI1TUBBBioGRID24189400 details
ERRFI1ESRRBBioGRID24189400 details
ERRFI1RNF123BioGRID29676528 details
ERRFI1ELAVL1BioGRID19322201 details