Entity Details

Primary name MICA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ29983
EntryNameMICA_HUMAN
FullNameMHC class I polypeptide-related sequence A
TaxID9606
Evidenceevidence at protein level
Length383
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesMICA

GO terms

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GOName
GO:0001913 T cell mediated cytotoxicity
GO:0002418 immune response to tumor cell
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006974 cellular response to DNA damage stimulus
GO:0009408 response to heat
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016032 viral process
GO:0019835 cytolysis
GO:0032815 negative regulation of natural killer cell activation
GO:0042267 natural killer cell mediated cytotoxicity
GO:0042742 defense response to bacterium
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
GO:0046629 gamma-delta T cell activation
GO:0046703 natural killer cell lectin-like receptor binding
GO:0050776 regulation of immune response
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011161 MHC class I-like antigen recognition-likeDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037055 MHC class I-like antigen recognition-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions