Entity Details

Primary name LIN41_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ2Q1W2
EntryNameLIN41_HUMAN
FullNameE3 ubiquitin-protein ligase TRIM71
TaxID9606
Evidenceevidence at protein level
Length868
SequenceStatuscomplete
DateCreated2007-03-06
DateModified2021-06-02

Ontological Relatives

GenesTRIM71

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000209 protein polyubiquitination
GO:0000932 P-body
GO:0001843 neural tube closure
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010586 miRNA metabolic process
GO:0010608 posttranscriptional regulation of gene expression
GO:0017148 negative regulation of translation
GO:0021915 neural tube development
GO:0030371 translation repressor activity
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035198 miRNA binding
GO:0035278 miRNA mediated inhibition of translation
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865 protein autoubiquitination
GO:0060964 regulation of gene silencing by miRNA
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0061630 ubiquitin protein ligase activity
GO:0072089 stem cell proliferation
GO:2000177 regulation of neural precursor cell proliferation
GO:2000637 positive regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001258 NHL repeatRepeatRepeat
IPR001298 Filamin/ABP280 repeatRepeatRepeat
IPR001841 Zinc finger, RING-typeDomainDomain
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR013017 NHL repeat, subgroupRepeatRepeat
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR017868 Filamin/ABP280 repeat-likeRepeatRepeat
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site

Diseases

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