Entity Details

Primary name ROBO1
Entity type gene
Source Source Link

Details

PrimaryID6091
RefseqGeneNG_011729
SymbolROBO1
Nameroundabout guidance receptor 1
Chromosome3
Location3p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-04-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsROBO1_HUMAN

GO terms

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GOName
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003180 aortic valve morphogenesis
GO:0003184 pulmonary valve morphogenesis
GO:0003272 endocardial cushion formation
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0008046 axon guidance receptor activity
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016199 axon midline choice point recognition
GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0030275 LRR domain binding
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033600 negative regulation of mammary gland epithelial cell proliferation
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035385 Roundabout signaling pathway
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction
GO:0035904 aorta development
GO:0042802 identical protein binding
GO:0043406 positive regulation of MAP kinase activity
GO:0050772 positive regulation of axonogenesis
GO:0050925 negative regulation of negative chemotaxis
GO:0060412 ventricular septum morphogenesis
GO:0070100 negative regulation of chemokine-mediated signaling pathway
GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
ROBO1SLIT2DIP, HPRD10102268 17848514 details
ROBO1SRGAP2DIP, HPRD11672528 26365803 details
ROBO1ARHGAP4DIP26365803 details
ROBO1SRGAP1BioGRID, HPRD, IntAct11672528 32203420 details
ROBO1TUBB3BioGRID, HPRD16169070 details
ROBO1MAPK14BioGRID20936779 details
ROBO1MAGEB6BioGRID32296183 details
ROBO1ROBO1IntAct12504588 details
ROBO1ROBO2HPRD, IntAct12504588 details
ROBO1TUBB4AIntAct16169070 details
ROBO1ROBO4mbinfo18948384 details
ROBO1USP33BioGRID, DIP19684588 19706539 29533940 30896071 details
ROBO1SLIT1HPRD10433822 details
ROBO1ABL1HPRD10892742 details
ROBO1BRK1IntAct24439376 details
ROBO1PARD6BBioGRID, IntAct26496610 details
ROBO1CDK2BioGRID, IntAct26496610 details
ROBO1GDPD5BioGRID, IntAct28514442 details
ROBO1HMGA1BioGRID, IntAct30021884 details
ROBO1CD9UniProt26686862 details
ROBO1SRGAP3BioGRID, IntAct32203420 details
ROBO1MAPK12BioGRID22939629 details
ROBO1ARPP19BioGRID26344197 details
ROBO1CTDSPLBioGRID27880917 details
ROBO1EGLN3BioGRID26972000 details
ROBO1HRASBioGRID30194290 details
ROBO1NRASBioGRID30194290 details
ROBO1KRASBioGRID30194290 34079125 details
ROBO1SQSTM1BioGRID30581152 details
ROBO1DNAJC5BioGRID33957083 details
ROBO1ARF6BioGRID34079125 details
ROBO1B3GAT1BioGRID34079125 details
ROBO1C11orf52BioGRID34079125 details
ROBO1CAV1BioGRID34079125 details
ROBO1EBAG9BioGRID34079125 details
ROBO1GJA1BioGRID34079125 details
ROBO1GJD3BioGRID34079125 details
ROBO1LAMTOR1BioGRID34079125 details
ROBO1LYNBioGRID34079125 details
ROBO1MARCKSBioGRID34079125 details
ROBO1OCLNBioGRID34079125 details
ROBO1RAB11ABioGRID34079125 details
ROBO1RAB35BioGRID34079125 details
ROBO1RAB5ABioGRID34079125 details
ROBO1RHOBBioGRID34079125 details
ROBO1STX4BioGRID34079125 details
ROBO1STX6BioGRID34079125 details
ROBO1STX7BioGRID34079125 details
ROBO1ZFPL1BioGRID34079125 details
ROBO1TRIM25BioGRID29117863 details
ROBO1VIRMABioGRID29507755 details
ROBO1MKRN2BioGRID32460013 details