Entity Details

Primary name CCL5
Entity type gene
Source Source Link

Details

PrimaryID6352
RefseqGeneNG_015990
SymbolCCL5
NameC-C motif chemokine ligand 5
Chromosome17
Location17q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCCL5_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002407 dendritic cell chemotaxis
GO:0002548 monocyte chemotaxis
GO:0002676 regulation of chronic inflammatory response
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004672 protein kinase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006887 exocytosis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007159 leukocyte cell-cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0009615 response to virus
GO:0009636 response to toxic substance
GO:0010536 positive regulation of activation of Janus kinase activity
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010820 positive regulation of T cell chemotaxis
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016004 phospholipase activator activity
GO:0019221 cytokine-mediated signaling pathway
GO:0030298 receptor signaling protein tyrosine kinase activator activity
GO:0030335 positive regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0031328 positive regulation of cellular biosynthetic process
GO:0031584 activation of phospholipase D activity
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031726 CCR1 chemokine receptor binding
GO:0031729 CCR4 chemokine receptor binding
GO:0031730 CCR5 chemokine receptor binding
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0034112 positive regulation of homotypic cell-cell adhesion
GO:0042056 chemoattractant activity
GO:0042102 positive regulation of T cell proliferation
GO:0042119 neutrophil activation
GO:0042327 positive regulation of phosphorylation
GO:0042379 chemokine receptor binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043491 protein kinase B signaling
GO:0043547 positive regulation of GTPase activity
GO:0043621 protein self-association
GO:0043922 negative regulation by host of viral transcription
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045070 positive regulation of viral genome replication
GO:0045071 negative regulation of viral genome replication
GO:0045089 positive regulation of innate immune response
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045785 positive regulation of cell adhesion
GO:0045948 positive regulation of translational initiation
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046817 chemokine receptor antagonist activity
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050796 regulation of insulin secretion
GO:0050863 regulation of T cell activation
GO:0051928 positive regulation of calcium ion transport
GO:0070098 chemokine-mediated signaling pathway
GO:0070233 negative regulation of T cell apoptotic process
GO:0070234 positive regulation of T cell apoptotic process
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090026 positive regulation of monocyte chemotaxis
GO:0098586 cellular response to virus
GO:1901214 regulation of neuron death
GO:2000406 positive regulation of T cell migration
GO:2000503 positive regulation of natural killer cell chemotaxis

Diseases

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Interactions

85 interactions

InteractorPartnerSourcesPublicationsLink
CCL5DPP4HPRD, MINT11390394 21314817 9516414 details
CCL5RELABioGRID, IntAct21988832 details
CCL5SLC2A5BioGRID, IntAct21988832 details
CCL5RANGAP1BioGRID, IntAct21988832 details
CCL5TRIP6BioGRID, IntAct21988832 details
CCL5EDC4BioGRID, IntAct21988832 details
CCL5CCR5bhf-ucl, BioGRID, HPRD, MINT10477718 11116158 11449371 14637022 23480650 28381538 8663314 9289016 details
CCL5CCL5bhf-ucl, DIP, HPRD, MINT15530372 21827949 23480650 28381538 7542919 8576227 9889151 details
CCL5APCBioGRID, MINT25640309 details
CCL5BAG4BioGRID, MINT25640309 details
CCL5BCAR3BioGRID, MINT25640309 details
CCL5CDH1MINT25640309 details
CCL5CHEK2BioGRID, MINT25640309 details
CCL5KRASBioGRID, MINT25640309 details
CCL5PALB2BioGRID, MINT25640309 details
CCL5PHBBioGRID, MINT25640309 details
CCL5PTPN1BioGRID, MINT25640309 details
CCL5TGFB1BioGRID, MINT25640309 details
CCL5WT1BioGRID, MINT25640309 details
CCL5TNFAIP6IntAct24501198 details
CCL5CCL17bhf-ucl, BioGRID28381538 details
CCL5PF4bhf-ucl, BioGRID, HPRD15459010 28381538 details
CCL5CXCL12bhf-ucl, BioGRID28381538 details
CCL5CXCL11bhf-ucl, BioGRID28381538 details
CCL5CCL2bhf-ucl, BioGRID28381538 details
CCL5CXCL9bhf-ucl, BioGRID28381538 details
CCL5PPBPbhf-ucl, BioGRID28381538 details
CCL5CXCL6bhf-ucl, BioGRID28381538 details
CCL5CXCL2bhf-ucl, BioGRID28381538 details
CCL5XCL2bhf-ucl, BioGRID28381538 details
CCL5XCL1bhf-ucl, BioGRID28381538 details
CCL5CCL28bhf-ucl, BioGRID28381538 details
CCL5CCL26bhf-ucl, BioGRID28381538 details
CCL5CCL25bhf-ucl, BioGRID28381538 details
CCL5CCL24bhf-ucl, BioGRID28381538 details
CCL5CCL21bhf-ucl, BioGRID28381538 details
CCL5CCL20bhf-ucl, BioGRID28381538 details
CCL5CCL16bhf-ucl, BioGRID28381538 details
CCL5CCL13bhf-ucl, BioGRID28381538 details
CCL5CCL11bhf-ucl, BioGRID28381538 details
CCL5CXCL10bhf-ucl, BioGRID28381538 details
CCL5CXCL17bhf-ucl, BioGRID28381538 details
CCL5CXCL14bhf-ucl, BioGRID28381538 details
CCL5CCL27bhf-ucl, BioGRID28381538 details
CCL5CCR1bhf-ucl, BioGRID, HPRD11116158 11449371 12270118 14637022 28381538 7545673 9289016 details
CCL5CXCL8BioGRID11509627 details
CCL5ACKR2BioGRID, HPRD9405404 details
CCL5CCR3BioGRID, HPRD11449371 8642344 9289016 details
CCL5CCR4BioGRID, HPRD12270118 8573157 details
CCL5VCANBioGRID, HPRD11083865 details
CCL5FZR1BioGRID25640309 details
CCL5SDC1BioGRID, HPRD14637022 details
CCL5SDC4BioGRID, HPRD14637022 details
CCL5PIGRHPRD11509627 details
CCL5IGFBP7HPRD12847218 details
CCL5ACKR4HPRD9469451 details
CCL5GRB2HPRD9009162 details
CCL5ACKR1HPRD12081195 17416748 details
CCL5SPRYD4BioGRID, IntAct28514442 details
CCL5NTMT1BioGRID, IntAct28514442 details
CCL5UBAC1BioGRID, IntAct28514442 details
CCL5S100A13BioGRID, IntAct28514442 details
CCL5SPATA20BioGRID, IntAct28514442 details
CCL5GPD1LBioGRID, IntAct28514442 details
CCL5AK4BioGRID, IntAct28514442 details
CCL5C4ABioGRID, IntAct28514442 details
CCL5C4BIntAct28514442 details
CCL5SNAI1IntAct25314079 details
CCL5GATA1IntAct10640782 details
CCL5GATA2IntAct10640782 details
CCL5GATA3IntAct10640782 details
CCL5HEY2IntAct33179750 details
CCL5HHEXIntAct33179750 details
CCL5ZNF710IntAct33179750 details
CCL5TFAP2BIntAct33179750 details
CCL5TFAP2AIntAct33179750 details
CCL5SOX14IntAct33179750 details
CCL5SIX6IntAct33179750 details
CCL5MLXIntAct33179750 details
CCL5IRX6IntAct33179750 details
CCL5IRX5IntAct33179750 details
CCL5HSF2IntAct33179750 details
CCL5HOXC8IntAct33179750 details
CCL5HOXA6IntAct33179750 details
CCL5ETS1IntAct33179750 details