Entity Details

Primary name IFIH1
Entity type gene
Source Source Link

Details

PrimaryID64135
RefseqGeneNG_011495
SymbolIFIH1
Nameinterferon induced with helicase C domain 1
Chromosome2
Location2q24.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-12-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIFIH1_HUMAN

GO terms

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GOName
GO:0003677 DNA binding
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008270 zinc ion binding
GO:0009597 detection of virus
GO:0009615 response to virus
GO:0016032 viral process
GO:0016579 protein deubiquitination
GO:0016787 hydrolase activity
GO:0016925 protein sumoylation
GO:0032480 negative regulation of type I interferon production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034344 regulation of type III interferon production
GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus
GO:0039530 MDA-5 signaling pathway
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0045087 innate immune response
GO:0051607 defense response to virus
GO:0060760 positive regulation of response to cytokine stimulus
GO:0071360 cellular response to exogenous dsRNA
GO:0098586 cellular response to virus

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
IFIH1KEAP1BioGRID, IntAct32296183 details
IFIH1RIOK3UniProt25865883 details
IFIH1TKFCDIP17600090 details
IFIH1APPBioGRID21832049 details
IFIH1USP3BioGRID24366338 details
IFIH1RNF123BioGRID27312109 details
IFIH1TRIM40BioGRID29117565 details
IFIH1TRIM65BioGRID28031478 details
IFIH1ZCCHC3BioGRID30193849 details
IFIH1MAVSBioGRID, DIP, IntAct, UniProt16127453 17600090 19416887 19881509 21903422 22301138 22623778 27312109 30193849 33372174 details
IFIH1DDX3XUniProt20127681 details
IFIH1IFIH1BioGRID, DIP, UniProt22160685 25865883 28031478 888800000136 details
IFIH1DHX58BioGRID, DIP17190814 888800000136 details
IFIH1RNF125DIP17460044 details
IFIH1IKBKEDIP17600090 details
IFIH1PRKRABioGRID, DIP28591694 details
IFIH1ISG15IntAct33727702 details
IFIH1SUMO1IntAct33727702 details
IFIH1YWHAHBioGRID, IntAct33727702 888800000136 details
IFIH1PIAS2BioGRID21156324 details
IFIH1PCBP2BioGRID19881509 details
IFIH1TSPAN6BioGRID22908223 details
IFIH1NLRC5BioGRID20434986 details
IFIH1USP21BioGRID24493797 details
IFIH1ARRDC4BioGRID28594402 details
IFIH1PPIABioGRID28594325 details
IFIH1TRIM25BioGRID30193849 details
IFIH1IDEBioGRID, IntAct21903422 details
IFIH1G3BP1BioGRID, IntAct26496610 details
IFIH1MPZL1BioGRID, IntAct28514442 details
IFIH1ATG12DIP17709747 details
IFIH1ATG5DIP17709747 details
IFIH1NACC1IntAct29251827 details
IFIH1DDHD2IntAct29251827 details
IFIH1UBR5IntAct29251827 details
IFIH1PCM1IntAct29251827 details
IFIH1SEC23IPIntAct29251827 details
IFIH1SUPT16HIntAct29251827 details
IFIH1ABHD10IntAct29251827 details
IFIH1TAX1BP1IntAct29251827 details
IFIH1SAMD4BIntAct29251827 details
IFIH1CAMK2DIntAct29251827 details
IFIH1CAMK2GIntAct29251827 details
IFIH1SSRP1IntAct29251827 details
IFIH1FAM168BIntAct29251827 details
IFIH1WIZIntAct29251827 details
IFIH1PSMD9IntAct29251827 details
IFIH1PPP1CAIntAct33727702 details
IFIH1PPP1CCIntAct33727702 details
IFIH1KIF20ABioGRID31586073 details