Entity Details

Primary name SRF
Entity type gene
Source Source Link

Details

PrimaryID6722
RefseqGene
SymbolSRF
Nameserum response factor
Chromosome6
Location6p21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-02-13
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsSRF_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001666 response to hypoxia
GO:0001707 mesoderm formation
GO:0001764 neuron migration
GO:0001829 trophectodermal cell differentiation
GO:0001947 heart looping
GO:0002011 morphogenesis of an epithelial sheet
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007160 cell-matrix adhesion
GO:0007507 heart development
GO:0007616 long-term memory
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0008306 associative learning
GO:0009636 response to toxic substance
GO:0009725 response to hormone
GO:0010669 epithelial structure maintenance
GO:0010735 positive regulation of transcription via serum response element binding
GO:0010736 serum response element binding
GO:0021766 hippocampus development
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb
GO:0030036 actin cytoskeleton organization
GO:0030155 regulation of cell adhesion
GO:0030168 platelet activation
GO:0030220 platelet formation
GO:0030336 negative regulation of cell migration
GO:0030878 thyroid gland development
GO:0031175 neuron projection development
GO:0031490 chromatin DNA binding
GO:0033561 regulation of water loss via skin
GO:0034097 response to cytokine
GO:0035855 megakaryocyte development
GO:0035912 dorsal aorta morphogenesis
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043149 stress fiber assembly
GO:0043589 skin morphogenesis
GO:0045059 positive thymic T cell selection
GO:0045214 sarcomere organization
GO:0045597 positive regulation of cell differentiation
GO:0045773 positive regulation of axon extension
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045987 positive regulation of smooth muscle contraction
GO:0046016 positive regulation of transcription by glucose
GO:0046716 muscle cell cellular homeostasis
GO:0048538 thymus development
GO:0048589 developmental growth
GO:0048666 neuron development
GO:0048821 erythrocyte development
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051150 regulation of smooth muscle cell differentiation
GO:0051491 positive regulation of filopodium assembly
GO:0055003 cardiac myofibril assembly
GO:0060055 angiogenesis involved in wound healing
GO:0060218 hematopoietic stem cell differentiation
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060292 long-term synaptic depression
GO:0060324 face development
GO:0060347 heart trabecula formation
GO:0060425 lung morphogenesis
GO:0060532 bronchus cartilage development
GO:0060534 trachea cartilage development
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0061029 eyelid development in camera-type eye
GO:0061145 lung smooth muscle development
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
GO:0070830 bicellular tight junction assembly
GO:0070878 primary miRNA binding
GO:0071333 cellular response to glucose stimulus
GO:0090009 primitive streak formation
GO:0090136 epithelial cell-cell adhesion
GO:0090398 cellular senescence
GO:1900222 negative regulation of amyloid-beta clearance
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

79 interactions

InteractorPartnerSourcesPublicationsLink
SRFMYOD1HPRD, MINT8617811 details
SRFMYOGBioGRID, HPRD, MINT10082523 8617811 details
SRFMRTFABioGRID, HPRD, IntAct12397177 14565952 15610731 17599918 21965288 details
SRFMYOCDBioGRID, HPRD, IntAct11439182 12397177 15014501 17360478 19342595 details
SRFALDH3A1BioGRID, IntAct21988832 details
SRFCIRBPBioGRID, IntAct21988832 details
SRFGTF2F1BioGRID, DIP, HPRD7854423 8106390 details
SRFELK4BioGRID, DIP, HPRD11406578 11846562 17200232 7854423 9271374 details
SRFPCNAUniProt26030842 details
SRFNCOA6BioGRID10847592 details
SRFPMLBioGRID, HPRD12622724 details
SRFCREBBPBioGRID, HPRD12622724 9388250 details
SRFRXRGBioGRID, HPRD11641790 details
SRFGATA4BioGRID, HPRD11003651 11158291 details
SRFRELBioGRID8670842 details
SRFRELABioGRID, HPRD8670842 details
SRFNFYABioGRID, HPRD10571058 details
SRFFLI1BioGRID, HPRD10606656 details
SRFELK1BioGRID, HPRD10606656 8083237 9010223 details
SRFTEAD1BioGRID, HPRD11136726 12061776 details
SRFSP1BioGRID10082523 details
SRFNCOR2BioGRID, HPRD10777532 details
SRFGTF2IBioGRID, HPRD12082086 9334314 9584171 details
SRFCD63BioGRID9271374 details
SRFATF6BioGRID, HPRD9271374 details
SRFCEBPBBioGRID, HPRD10318842 11500490 9032301 details
SRFHDAC4BioGRID12663674 details
SRFKAT5BioGRID15591049 details
SRFCSNK2A1BioGRID, HPRD1740119 2046671 details
SRFSRFBioGRID, HPRD11406578 2046671 2108863 8083237 details
SRFKDM6ABioGRID22192413 details
SRFTRIM63BioGRID15802564 details
SRFUBE2IBioGRID12788062 details
SRFSHBGBioGRID15862967 details
SRFPRKDCBioGRID, HPRD8407951 details
SRFNFKB1BioGRID2108863 details
SRFSRFBP1BioGRID, HPRD15492011 8083237 details
SRFZIC3BioGRID17468179 details
SRFFHL1BioGRID, HPRD15610731 details
SRFFHL2BioGRID, HPRD15610731 details
SRFTRIP4BioGRID12077347 details
SRFNCOA1BioGRID, HPRD9786846 details
SRFRARABioGRID11641790 details
SRFRXRABioGRID, HPRD11641790 details
SRFFOXK1BioGRID17670796 details
SRFFOXG1BioGRID17670796 details
SRFMRTFBBioGRID, HPRD, IntAct12397177 14565952 details
SRFSSRP1BioGRID, HPRD10336466 details
SRFNKX3-1BioGRID, HPRD10993896 details
SRFSMARCA4BioGRID17599918 19342595 details
SRFHDAC3BioGRID17158926 details
SRFSMAD7BioGRID16690609 details
SRFEPC1BioGRID19359245 details
SRFPELP1BioGRID15456770 details
SRFPRRX1HPRD9334314 details
SRFSRCHPRD9786846 details
SRFOGTHPRD1512232 details
SRFNKX2-5HPRD8887666 details
SRFCASP3HPRD11387340 details
SRFHMGA1HPRD9545312 details
SRFETV4HPRD7796532 details
SRFCRIP2HPRD12530967 details
SRFRPS6KA1HPRD10318869 10753652 8413226 details
SRFCASP7HPRD11387340 details
SRFNKX2-3HPRD11457859 details
SRFPYCARDHPRD10847592 details
SRFHOPXHPRD12297045 details
SRFMAPKAPK2HPRD10318869 10753652 12171911 8413226 details
SRFBARX2HPRD11278942 details
SRFFHL3HPRD15610731 details
SRFFHL5HPRD15610731 details
SRFCREB1HPRD7551568 9388250 details
SRFCASP6HPRD11387340 details
SRFCASP8HPRD11387340 details
SRFCASP9HPRD11387340 details
SRFMINPP1HPRD18497331 details
SRFTCF3HPRD8617811 details
SRFHNRNPLBioGRID28611215 details
SRFHNRNPH1BioGRID26760575 details