Entity Details

Primary name TBX2
Entity type gene
Source Source Link

Details

PrimaryID6909
RefseqGene
SymbolTBX2
NameT-box transcription factor 2
Chromosome17
Location17q23.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-11-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTBX2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0001947 heart looping
GO:0003148 outflow tract septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003203 endocardial cushion morphogenesis
GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003272 endocardial cushion formation
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007219 Notch signaling pathway
GO:0007521 muscle cell fate determination
GO:0007569 cell aging
GO:0008016 regulation of heart contraction
GO:0008284 positive regulation of cell population proliferation
GO:0035050 embryonic heart tube development
GO:0035909 aorta morphogenesis
GO:0036302 atrioventricular canal development
GO:0042733 embryonic digit morphogenesis
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048738 cardiac muscle tissue development
GO:0051145 smooth muscle cell differentiation
GO:0060021 roof of mouth development
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060465 pharynx development
GO:0060560 developmental growth involved in morphogenesis
GO:0060596 mammary placode formation
GO:0072105 ureteric peristalsis
GO:0090398 cellular senescence
GO:1901208 negative regulation of heart looping
GO:1901211 negative regulation of cardiac chamber formation
GO:1905072 cardiac jelly development
GO:1905222 atrioventricular canal morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

19 interactions

InteractorPartnerSourcesPublicationsLink
TBX2CYSRT1BioGRID, IntAct32296183 details
TBX2TNPO2BioGRID, IntAct32296183 details
TBX2TTC19BioGRID, IntAct32296183 details
TBX2ATXN1LBioGRID, IntAct32296183 details
TBX2MEIS2BioGRID, IntAct32296183 details
TBX2CIDEBBioGRID, IntAct32296183 details
TBX2CNOT2BioGRID, IntAct32296183 details
TBX2LMO2BioGRID, IntAct32296183 details
TBX2CEBPEBioGRID, IntAct20211142 details
TBX2LZTR1BioGRID, IntAct20211142 details
TBX2PMLBioGRID, MINT22002537 details
TBX2EGR1BioGRID20348948 details
TBX2SOX2BioGRID23674600 details
TBX2DDB2BioGRID28035050 details
TBX2NKX2-5HPRD12023302 details
TBX2TEAD2BioGRID, MINT25609649 details
TBX2ESR1BioGRID, IntAct31527615 details
TBX2SP100BioGRID31753913 details
TBX2CICBioGRID29844126 details