Entity Details

Primary name C5
Entity type gene
Source Source Link

Details

PrimaryID727
RefseqGeneNG_007364
SymbolC5
Namecomplement C5
Chromosome9
Location9q33.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-07-04
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCO5_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001701 in utero embryonic development
GO:0004866 endopeptidase inhibitor activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0005615 extracellular space
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008009 chemokine activity
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010760 negative regulation of macrophage chemotaxis
GO:0019835 cytolysis
GO:0030449 regulation of complement activation
GO:0032722 positive regulation of chemokine production
GO:0045766 positive regulation of angiogenesis
GO:0070062 extracellular exosome

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
C5CREB3L1BioGRID, IntAct25416956 details
C5POU6F2BioGRID, IntAct32296183 details
C5EBPBioGRID, IntAct32296183 details
C5AQP6BioGRID, IntAct32296183 details
C5PGRMC2BioGRID, IntAct32296183 details
C5NEMP1BioGRID, IntAct32296183 details
C5SSMEM1BioGRID, IntAct32296183 details
C5ANKS6BioGRID, IntAct32296183 details
C5CPLX4BioGRID, IntAct32296183 details
C5MMGT1BioGRID, IntAct32296183 details
C5KELBioGRID, IntAct32296183 details
C5CFHR1IntAct19528535 details
C5C6BioGRID, HPRD, IntAct1387399 26841837 2808363 30552328 details
C5C7BioGRID, HPRD, IntAct1387399 26841837 30552328 details
C5C8BBioGRID, HPRD, IntAct26841837 30552328 3624872 details
C5C5AR1BioGRID, HPRD9553099 details
C5CPB2BioGRID11939578 details
C5C3BioGRID, HPRD11367533 details
C5LMNABioGRID24623722 details
C5VEZTBioGRID32296183 details
C5C5HPRD3624872 8175701 details
C5C2HPRD12878586 8175701 details
C5CPN1HPRD11939578 details
C5C8AIntAct26841837 30552328 details
C5C8GIntAct26841837 30552328 details
C5C9IntAct26841837 30552328 details
C5CTSBBioGRID26208400 details
C5NR3C1BioGRID31182584 details