Entity Details

Primary name UCHL1
Entity type gene
Source Source Link

Details

PrimaryID7345
RefseqGeneNG_012931
SymbolUCHL1
Nameubiquitin C-terminal hydrolase L1
Chromosome4
Location4p13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1996-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsUCHL1_HUMAN

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0008242 omega peptidase activity
GO:0016241 regulation of macroautophagy
GO:0016579 protein deubiquitination
GO:0016874 ligase activity
GO:0031625 ubiquitin protein ligase binding
GO:0031694 alpha-2A adrenergic receptor binding
GO:0043130 ubiquitin binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043407 negative regulation of MAP kinase activity

Diseases

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Interactions

214 interactions

InteractorPartnerSourcesPublicationsLink
UCHL1CBX1BioGRID, HPRD, IntAct16169070 32814053 details
UCHL1NEDD8BioGRID, HPRD, IntAct16169070 32814053 details
UCHL1APPBioGRID, IntAct16049941 25466238 32814053 details
UCHL1EIF1BIntAct17353931 32814053 details
UCHL1ATG5IntAct17353931 32814053 details
UCHL1TRAF6BioGRID, IntAct17353931 23717208 32814053 details
UCHL1IKBKEIntAct17353931 32814053 details
UCHL1COPS5BioGRID, HPRD, IntAct12082530 details
UCHL1UBE2IBioGRID, HPRD, IntAct12082530 details
UCHL1RANBP9BioGRID, HPRD, IntAct12082530 details
UCHL1CDKN1BBioGRID, HPRD, IntAct12082530 details
UCHL1USP21BioGRID, IntAct19615732 22626734 32814053 details
UCHL1EGFRBioGRID, IntAct20029029 31980649 32042339 32494592 details
UCHL1NCAM1BioGRID, MINT23061666 details
UCHL1AKT1BioGRID, MINT16027165 25640309 details
UCHL1TERF2IPbhf-ucl, BioGRID21044950 29126443 details
UCHL1TINF2bhf-ucl, BioGRID21044950 details
UCHL1PDZK1IP1IntAct32814053 details
UCHL1COPS3IntAct32814053 details
UCHL1RNF112IntAct32814053 details
UCHL1BRK1IntAct32814053 details
UCHL1TP53BioGRID, IntAct18666234 20395212 29126443 32814053 details
UCHL1TERF2BioGRID, IntAct29126443 32814053 details
UCHL1TRIM21IntAct32814053 details
UCHL1RANIntAct32814053 details
UCHL1NVLIntAct32814053 details
UCHL1LAMP2BioGRID, HPRD, IntAct18550537 18635949 32814053 details
UCHL1UBE2KIntAct32814053 details
UCHL1ATF3IntAct32814053 details
UCHL1BIRC5IntAct32814053 details
UCHL1AP2B1IntAct32814053 details
UCHL1IQSEC1IntAct32814053 details
UCHL1UBAC1IntAct32814053 details
UCHL1L3MBTL3IntAct32814053 details
UCHL1ZC3HC1IntAct32814053 details
UCHL1LSM8IntAct32814053 details
UCHL1ARFGAP1IntAct32814053 details
UCHL1EVLIntAct32814053 details
UCHL1ENKURIntAct32814053 details
UCHL1RHEBL1IntAct32814053 details
UCHL1HNRNPLLIntAct32814053 details
UCHL1LDHAL6BIntAct32814053 details
UCHL1UBCBioGRID, HPRD16169070 20439756 20622874 22284438 23801757 2532544 27066941 27501351 28338014 28935764 29576527 31494268 9521656 details
UCHL1SMN1BioGRID20713032 details
UCHL1HSPA8BioGRID, HPRD18550537 18635949 details
UCHL1HSP90AA1BioGRID, HPRD18550537 18635949 32120844 details
UCHL1ADRA2ABioGRID19477270 details
UCHL1ADRA2BBioGRID19477270 details
UCHL1ADRA2CBioGRID19477270 details
UCHL1ADRB2BioGRID19477270 details
UCHL1TRIM63BioGRID22626734 details
UCHL1TRIM54BioGRID22626734 details
UCHL1USP15BioGRID22626734 details
UCHL1USP28BioGRID22626734 details
UCHL1TNFRSF1ABioGRID24980434 details
UCHL1PLA2G2ABioGRID22118674 details
UCHL1PRKNBioGRID25403879 details
UCHL1AKT2BioGRID28636190 details
UCHL1UBBIntAct16169070 details
UCHL1VHLIntAct17353931 details
UCHL1EIF6IntAct17353931 details
UCHL1MCCIntAct17353931 details
UCHL1TNIKIntAct17353931 details
UCHL1FMR1IntAct31413325 details
UCHL1MYCBP2MINT21653829 details
UCHL1CTNNB1BioGRID19536331 details
UCHL1MDM2BioGRID20395212 details
UCHL1CDKN2ABioGRID20395212 details
UCHL1TUBA1ABioGRID18250096 details
UCHL1DDB1BioGRID23297343 details
UCHL1RPTORBioGRID23297343 details
UCHL1CDK1BioGRID23543736 details
UCHL1CDK4BioGRID23543736 details
UCHL1CDK5BioGRID23543736 details
UCHL1CDK6BioGRID23543736 details
UCHL1PMAIP1BioGRID23499448 details
UCHL1TRAF3BioGRID23717208 details
UCHL1NMRAL1BioGRID24763515 details
UCHL1DERL1BioGRID28137758 details
UCHL1MITFBioGRID28392346 details
UCHL1AIPBioGRID31042473 details
UCHL1BCL6BioGRID31042473 details
UCHL1CCNB1BioGRID31906456 details
UCHL1CTTNBioGRID32120844 details
UCHL1ANXA6BioGRID32606430 details
UCHL1HSPA5BioGRID32606430 details
UCHL1CPT1BBioGRID32606430 details
UCHL1PYGBBioGRID32606430 details
UCHL1TUFMBioGRID32606430 details
UCHL1CSRP3BioGRID32606430 details
UCHL1SMAD2BioGRID32371398 details
UCHL1SMAD3BioGRID32371398 details
UCHL1SMAD4BioGRID32371398 details
UCHL1KRT17BioGRID, IntAct19615732 details
UCHL1CCDC14BioGRID, IntAct19615732 details
UCHL1KRT4BioGRID, IntAct19615732 details
UCHL1IQCB1BioGRID, IntAct21565611 details
UCHL1IFI16BioGRID, IntAct25665578 details
UCHL1AIM2BioGRID, IntAct25665578 details
UCHL1PYHIN1BioGRID, IntAct25665578 details
UCHL1OTUB1IntAct26752685 details
UCHL1PPTC7BioGRID, IntAct28330616 details
UCHL1PHOSPHO1BioGRID, IntAct28330616 details
UCHL1STAT1MINT26966684 details
UCHL1RPS6BioGRID, IntAct29568061 details
UCHL1DLSTBioGRID, IntAct29128334 details
UCHL1SOD1BioGRID, IntAct29128334 31536960 details
UCHL1LRRK2BioGRID, IntAct31046837 details
UCHL1CFTRIntAct29924966 details
UCHL1CDK2BioGRID21319273 details
UCHL1WDR82BioGRID22939629 32120844 details
UCHL1ERN1BioGRID25225294 details
UCHL1CUL7BioGRID24711643 details
UCHL1NTRK1BioGRID25921289 details
UCHL1ACTC1BioGRID30890647 details
UCHL1FDXRBioGRID31536960 details
UCHL1OXCT1BioGRID31536960 details
UCHL1GRPEL1BioGRID31536960 details
UCHL1HDHD3BioGRID31536960 details
UCHL1FHBioGRID31536960 details
UCHL1ACO2BioGRID31536960 details
UCHL1NDUFAB1BioGRID31536960 details
UCHL1SPRBioGRID31536960 details
UCHL1FAHD2ABioGRID31536960 details
UCHL1SUCLA2BioGRID31536960 details
UCHL1POLDIP2BioGRID31536960 details
UCHL1AIFM1BioGRID31536960 details
UCHL1HINT2BioGRID31536960 details
UCHL1GRHPRBioGRID31536960 details
UCHL1THEM4BioGRID31536960 details
UCHL1SUCLG1BioGRID31536960 details
UCHL1STXBP1BioGRID31536960 details
UCHL1CLIC1BioGRID31536960 details
UCHL1DDAH1BioGRID31536960 details
UCHL1ENO1BioGRID31536960 32120844 details
UCHL1GSTP1BioGRID31536960 details
UCHL1GATD3BioGRID31536960 details
UCHL1CLIC4BioGRID31536960 details
UCHL1GCSHBioGRID31536960 details
UCHL1GLOD4BioGRID31536960 details
UCHL1IDH2BioGRID31536960 details
UCHL1LACTB2BioGRID31536960 details
UCHL1PARK7BioGRID31536960 details
UCHL1PDP1BioGRID31536960 details
UCHL1PGM1BioGRID31536960 details
UCHL1PRDX6BioGRID31536960 details
UCHL1BIRC3BioGRID30948266 details
UCHL1PLEKHA4BioGRID31091453 details
UCHL1NGBBioGRID31405213 details
UCHL1KIF20ABioGRID31586073 details
UCHL1PRC1BioGRID31586073 details
UCHL1NDNBioGRID32529326 details
UCHL1MYH9BioGRID32120844 details
UCHL1MYH10BioGRID32120844 details
UCHL1MYH11BioGRID32120844 details
UCHL1UCHL1BioGRID32120844 details
UCHL1DBN1BioGRID32120844 details
UCHL1FLG2BioGRID32120844 details
UCHL1TPM4BioGRID32120844 details
UCHL1TPM3BioGRID32120844 details
UCHL1MYO1BBioGRID32120844 details
UCHL1YWHAZBioGRID32120844 details
UCHL1FUSBioGRID32120844 details
UCHL1HSP90AB1BioGRID32120844 details
UCHL1DCDBioGRID32120844 details
UCHL1METTL3BioGRID32120844 details
UCHL1RPS4XBioGRID32120844 details
UCHL1TUBB2BBioGRID32120844 details
UCHL1PLA2G4BBioGRID32120844 details
UCHL1RPL17BioGRID32120844 details
UCHL1RPS27ABioGRID32120844 details
UCHL1CIP2ABioGRID32120844 details
UCHL1TRAF4BioGRID32120844 details
UCHL1CCDC66BioGRID32120844 details
UCHL1C1orf68BioGRID32120844 details
UCHL1HRNRBioGRID32120844 details
UCHL1USP17L24BioGRID32120844 details
UCHL1RPL18ABioGRID32120844 details
UCHL1BAZ1ABioGRID32120844 details
UCHL1ALBBioGRID32120844 details
UCHL1MYO1CBioGRID32120844 details
UCHL1MRRFBioGRID32120844 details
UCHL1PDE8BBioGRID32120844 details
UCHL1TGM4BioGRID32120844 details
UCHL1LAMA3BioGRID32120844 details
UCHL1CD163BioGRID32120844 details
UCHL1RXYLT1BioGRID32120844 details
UCHL1SLC22A4BioGRID32120844 details
UCHL1SYTL4BioGRID32120844 details
UCHL1SPATA7BioGRID32120844 details
UCHL1IL16BioGRID32120844 details
UCHL1KCNB1BioGRID32120844 details
UCHL1DNAH12BioGRID32120844 details
UCHL1FKBP10BioGRID32120844 details
UCHL1SYT15BioGRID32120844 details
UCHL1SCN3ABioGRID32120844 details
UCHL1ZNF44BioGRID32120844 details
UCHL1ZNF792BioGRID32120844 details
UCHL1C9orf131BioGRID32120844 details
UCHL1ANKRD6BioGRID32120844 details
UCHL1SYNMBioGRID32120844 details
UCHL1RB1BioGRID32120844 details
UCHL1DSPBioGRID32120844 details
UCHL1USP8BioGRID32120844 details
UCHL1ANKRD31BioGRID32120844 details
UCHL1CYS1BioGRID32120844 details
UCHL1DSG1BioGRID32120844 details
UCHL1ATXN2LBioGRID32120844 details
UCHL1STAT4BioGRID32120844 details
UCHL1DNMT1BioGRID32120844 details
UCHL1BAG5BioGRID32850835 details
UCHL1CD274BioGRID32941674 details
UCHL1ANAPC2BioGRID34079125 details
UCHL1SQSTM1BioGRID34079125 details