Entity Details

Primary name WNT2
Entity type gene
Source Source Link

Details

PrimaryID7472
RefseqGene
SymbolWNT2
NameWnt family member 2
Chromosome7
Location7q31.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsWNT2_HUMAN

GO terms

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GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002088 lens development in camera-type eye
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007267 cell-cell signaling
GO:0008284 positive regulation of cell population proliferation
GO:0016055 Wnt signaling pathway
GO:0022008 neurogenesis
GO:0030182 neuron differentiation
GO:0030324 lung development
GO:0031232 extrinsic component of external side of plasma membrane
GO:0033278 cell proliferation in midbrain
GO:0045165 cell fate commitment
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048018 receptor ligand activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0050769 positive regulation of neurogenesis
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060070 canonical Wnt signaling pathway
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0060492 lung induction
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060716 labyrinthine layer blood vessel development
GO:0061072 iris morphogenesis
GO:0061180 mammary gland epithelium development
GO:0062023 collagen-containing extracellular matrix
GO:0071300 cellular response to retinoic acid
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1904948 midbrain dopaminergic neuron differentiation
GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1990909 Wnt signalosome

Diseases

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Interactions

12 interactions

InteractorPartnerSourcesPublicationsLink
WNT2AQP5BioGRID, IntAct21988832 details
WNT2HCKBioGRID, IntAct21988832 details
WNT2UQCR11BioGRID, IntAct21988832 details
WNT2RRAGCBioGRID, IntAct21988832 details
WNT2SFRP1bhf-ucl, BioGRID, HPRD10347172 details
WNT2PITX2BioGRID23250740 details
WNT2FZD1HPRD10557084 details
WNT2FZD9HPRD12138115 details
WNT2WNT3AHPRD10557084 details
WNT2HSPA5BioGRID, IntAct28514442 details
WNT2NME7BioGRID26186194 details
WNT2DCAF4BioGRID30945288 details