Entity Details

Primary name PYDC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ56P42
EntryNamePYDC2_HUMAN
FullNamePyrin domain-containing protein 2
TaxID9606
Evidenceevidence at protein level
Length97
SequenceStatuscomplete
DateCreated2008-09-02
DateModified2021-06-02

Ontological Relatives

GenesPYDC2

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032691 negative regulation of interleukin-1 beta production
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:1900226 negative regulation of NLRP3 inflammasome complex assembly
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004020 DAPIN domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions