Entity Details

Primary name HAVCR2
Entity type gene
Source Source Link

Details

PrimaryID84868
RefseqGeneNG_030444
SymbolHAVCR2
Namehepatitis A virus cellular receptor 2
Chromosome5
Location5q33.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-28
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsHAVR2_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0002250 adaptive immune response
GO:0002281 macrophage activation involved in immune response
GO:0002519 natural killer cell tolerance induction
GO:0002652 regulation of tolerance induction dependent upon immune response
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005769 early endosome
GO:0006954 inflammatory response
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030886 negative regulation of myeloid dendritic cell activation
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032687 negative regulation of interferon-alpha production
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032712 negative regulation of interleukin-3 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032722 positive regulation of chemokine production
GO:0032729 positive regulation of interferon-gamma production
GO:0032732 positive regulation of interleukin-1 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032815 negative regulation of natural killer cell activation
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034154 toll-like receptor 7 signaling pathway
GO:0034162 toll-like receptor 9 signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0043032 positive regulation of macrophage activation
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0046872 metal ion binding
GO:0050830 defense response to Gram-positive bacterium
GO:0060135 maternal process involved in female pregnancy
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071656 negative regulation of granulocyte colony-stimulating factor production
GO:1900425 negative regulation of defense response to bacterium
GO:1900426 positive regulation of defense response to bacterium
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000521 negative regulation of immunological synapse formation
GO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Diseases

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Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
HAVCR2SEC22ABioGRID, IntAct32296183 details
HAVCR2TMEM86ABioGRID, IntAct32296183 details
HAVCR2APPBioGRID21832049 details
HAVCR2LCKBioGRID, UniProt22863785 26492563 details
HAVCR2CEACAM1DIP25363763 details
HAVCR2BAG6BioGRID22863785 details
HAVCR2HAVCR2HPRD14556006 details
HAVCR2PTENUniProt26492563 details
HAVCR2PLCG1UniProt26492563 details
HAVCR2SH2D2AUniProt26492563 details
HAVCR2SH3BP2UniProt26492563 details
HAVCR2FYNUniProt26492563 details
HAVCR2PIK3R1BioGRID, IntAct, UniProt26492563 28514442 details
HAVCR2SYKUniProt26492563 details
HAVCR2ZAP70UniProt26492563 details
HAVCR2LCP2UniProt26492563 details
HAVCR2VAV1UniProt26492563 details
HAVCR2SH2B3UniProt26492563 details
HAVCR2UTP18BioGRID, IntAct28514442 details
HAVCR2NISCHBioGRID, IntAct28514442 details
HAVCR2TTF2BioGRID, IntAct28514442 details
HAVCR2NOCTBioGRID, IntAct28514442 details
HAVCR2DIP2BBioGRID, IntAct28514442 details
HAVCR2CLDND1BioGRID, IntAct28514442 details
HAVCR2ATP13A2BioGRID, IntAct28514442 details
HAVCR2IL1RAPBioGRID, IntAct28514442 details
HAVCR2PIGMBioGRID, IntAct28514442 details
HAVCR2ZDHHC5BioGRID, IntAct28514442 details
HAVCR2LGR4BioGRID, IntAct28514442 details
HAVCR2PKP2BioGRID, IntAct28514442 details
HAVCR2AGPAT1BioGRID, IntAct28514442 details
HAVCR2PKP4BioGRID, IntAct28514442 details
HAVCR2MYADMBioGRID, IntAct28514442 details
HAVCR2SLC22A18BioGRID, IntAct28514442 details
HAVCR2UTP4BioGRID, IntAct28514442 details
HAVCR2PIK3R3BioGRID, IntAct28514442 details
HAVCR2CERKBioGRID, IntAct28514442 details
HAVCR2PI4K2BBioGRID, IntAct28514442 details
HAVCR2WDR36BioGRID, IntAct28514442 details
HAVCR2EXPH5BioGRID, IntAct28514442 details
HAVCR2AGBL5BioGRID, IntAct28514442 details
HAVCR2KDM1BBioGRID, IntAct28514442 details
HAVCR2PNPLA6BioGRID, IntAct28514442 details
HAVCR2DENND6ABioGRID, IntAct28514442 details
HAVCR2PLEKHH3BioGRID, IntAct28514442 details
HAVCR2GOLGA7BioGRID, IntAct28514442 details
HAVCR2CNKSR3BioGRID, IntAct28514442 details
HAVCR2PKN3BioGRID, IntAct28514442 details
HAVCR2LPCAT4BioGRID, IntAct28514442 details
HAVCR2MAP3K21BioGRID, IntAct28514442 details
HAVCR2WDR44BioGRID, IntAct28514442 details
HAVCR2TIGD5BioGRID, IntAct28514442 details
HAVCR2PKN2BioGRID, IntAct28514442 details
HAVCR2SNX17BioGRID, IntAct28514442 details
HAVCR2DIP2ABioGRID, IntAct28514442 details
HAVCR2MELKBioGRID, IntAct28514442 details
HAVCR2MTMR1BioGRID, IntAct28514442 details
HAVCR2SLC20A2BioGRID, IntAct28514442 details
HAVCR2CNTNAP1BioGRID, IntAct28514442 details
HAVCR2DGKQBioGRID, IntAct28514442 details
HAVCR2PIK3CBBioGRID, IntAct28514442 details
HAVCR2PIK3CABioGRID, IntAct28514442 details
HAVCR2TSPAN7BioGRID, IntAct28514442 details
HAVCR2PIGABioGRID, IntAct28514442 details
HAVCR2BMPR1ABioGRID, IntAct28514442 details
HAVCR2TYK2BioGRID, IntAct28514442 details
HAVCR2ACVR2ABioGRID, IntAct28514442 details
HAVCR2JAK1BioGRID, IntAct28514442 details
HAVCR2CISD3BioGRID, IntAct28514442 details
HAVCR2ERBB2BioGRID, IntAct28514442 details
HAVCR2ZMYM6BioGRID, IntAct28514442 details
HAVCR2SBF1BioGRID, IntAct28514442 details
HAVCR2RHOBTB3BioGRID, IntAct28514442 details
HAVCR2MYO1DBioGRID, IntAct28514442 details
HAVCR2PHLPP1BioGRID, IntAct28514442 details
HAVCR2PLD2BioGRID, IntAct28514442 details
HAVCR2PIK3R2BioGRID, IntAct28514442 details
HAVCR2PIK3C2ABioGRID, IntAct28514442 details
HAVCR2TCAF2BioGRID, IntAct28514442 details
HAVCR2DDX58BioGRID32513696 details