Entity Details

Primary name SYEM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5JPH6
EntryNameSYEM_HUMAN
FullNameProbable glutamate--tRNA ligase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length523
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesEARS2

GO terms

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GOName
GO:0000049 tRNA binding
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006424 glutamyl-tRNA aminoacylation
GO:0008270 zinc ion binding
GO:0050561 glutamate-tRNA(Gln) ligase activity
GO:0070127 tRNA aminoacylation for mitochondrial protein translation

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR000924 Glutamyl/glutaminyl-tRNA synthetaseFamilyFamily
IPR001412 Aminoacyl-tRNA synthetase, class I, conserved siteSiteConserved site
IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrialFamilyFamily
IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-bindingFamilyHomologous superfamily
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domainDomainDomain
IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2FamilyHomologous superfamily
IPR033910 Glutamyl-tRNA synthetaseDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SYEM_HUMANOGT1_HUMANBioGRID32994395 details
SYEM_HUMANGRSF1_HUMANBioGRID29395067 details