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Entity Details
Primary name
ESPL1
Entity type
gene
Source
Source Link
Details
PrimaryID
9700
RefseqGene
Symbol
ESPL1
Name
extra spindle pole bodies like 1, separase
Chromosome
12
Location
12q13.13
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
2000-02-20
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
ESPL1_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000070
mitotic sister chromatid segregation
GO:0000212
meiotic spindle organization
GO:0000281
mitotic cytokinesis
GO:0003824
catalytic activity
GO:0004197
cysteine-type endopeptidase activity
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005813
centrosome
GO:0005829
cytosol
GO:0006915
apoptotic process
GO:0008234
cysteine-type peptidase activity
GO:0040001
establishment of mitotic spindle localization
GO:0045143
homologous chromosome segregation
GO:0045842
positive regulation of mitotic metaphase/anaphase transition
GO:0045875
negative regulation of sister chromatid cohesion
GO:0051307
meiotic chromosome separation
GO:0072686
mitotic spindle
Diseases
Show/Hide Table
Interactions
53 interactions
Interactor
Partner
Sources
Publications
Link
ESPL1
PTTG1
BioGRID, IntAct, MINT
19117984
20360068
24781523
25750436
26186194
26496610
28514442
details
ESPL1
MTNR1B
BioGRID, IntAct
26514267
details
ESPL1
RAD21
DIP
15737063
details
ESPL1
RFFL
BioGRID
22626734
details
ESPL1
PJA1
BioGRID
22626734
details
ESPL1
TRIM63
BioGRID
22626734
details
ESPL1
TRIM55
BioGRID
22626734
details
ESPL1
USP21
BioGRID
22626734
details
ESPL1
USP28
BioGRID
22626734
details
ESPL1
CCNB1
BioGRID, MINT
24781523
25750436
details
ESPL1
PPP2R1A
BioGRID
24781523
details
ESPL1
PPP2R5A
BioGRID
24781523
details
ESPL1
PPP2CA
BioGRID, MINT
24781523
details
ESPL1
PPP2R1B
MINT
24781523
details
ESPL1
KIF2C
BioGRID, IntAct
26496610
details
ESPL1
TTK
BioGRID, IntAct
26496610
details
ESPL1
ACKR3
BioGRID, IntAct
26496610
details
ESPL1
IBTK
BioGRID, IntAct
26496610
details
ESPL1
HNRNPU
BioGRID, IntAct
26496610
details
ESPL1
FBXO7
BioGRID, IntAct
26496610
details
ESPL1
SGTB
BioGRID, IntAct
26496610
details
ESPL1
HNRNPD
BioGRID, IntAct
26496610
details
ESPL1
USP11
BioGRID, IntAct
26496610
details
ESPL1
TENT5A
BioGRID, IntAct
28514442
details
ESPL1
CDC16
BioGRID, IntAct
28514442
details
ESPL1
TULP2
BioGRID, IntAct
28514442
details
ESPL1
IL17RA
BioGRID, IntAct
28514442
details
ESPL1
GATD1
BioGRID, IntAct
28514442
details
ESPL1
LYPD4
BioGRID, IntAct
28514442
details
ESPL1
DNAJC7
BioGRID, IntAct
28514442
33957083
details
ESPL1
IARS2
BioGRID, IntAct
28514442
details
ESPL1
GFOD1
BioGRID, IntAct
26186194
28514442
details
ESPL1
FBXO4
BioGRID, IntAct
28514442
details
ESPL1
HSPA8
BioGRID, IntAct
29568061
details
ESPL1
CCT7
BioGRID, IntAct
30021884
details
ESPL1
HDAC2
BioGRID, IntAct
30021884
details
ESPL1
VCP
BioGRID
23383273
details
ESPL1
XPO1
BioGRID
26673895
details
ESPL1
FUZ
BioGRID
28514442
details
ESPL1
DUSP2
BioGRID
28675297
details
ESPL1
LMBR1L
BioGRID
31073040
details
ESPL1
PLEKHA4
BioGRID
31091453
details
ESPL1
FKBP8
BioGRID
32877691
details
ESPL1
HAX1
BioGRID
32877691
details
ESPL1
DNAJA2
BioGRID
33957083
details
ESPL1
DNAJC2
BioGRID
33957083
details
ESPL1
PRKACA
BioGRID
33957083
details
ESPL1
CAMSAP2
BioGRID
34079125
details
ESPL1
DCTN1
BioGRID
34079125
details
ESPL1
TRIM36
BioGRID
34079125
details
ESPL1
MOV10
BioGRID
22658674
details
ESPL1
NXF1
BioGRID
22658674
details
ESPL1
VIRMA
BioGRID
29507755
details
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