Entity Details

Primary name MARH8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T0T0
EntryNameMARH8_HUMAN
FullNameE3 ubiquitin-protein ligase MARCHF8
TaxID9606
Evidenceevidence at protein level
Length291
SequenceStatuscomplete
DateCreated2007-02-06
DateModified2021-06-02

Ontological Relatives

GenesMARCHF8

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0002250 adaptive immune response
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0006955 immune response
GO:0008270 zinc ion binding
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0042287 MHC protein binding
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle membrane
Early endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR011016 Zinc finger, RING-CH-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily

Diseases

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