Entity Details

Primary name RBM12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NTZ6
EntryNameRBM12_HUMAN
FullNameRNA-binding protein 12
TaxID9606
Evidenceevidence at protein level
Length932
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesRBM12

GO terms

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GOName
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0043484 regulation of RNA splicing
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034591 RBM12, RNA recognition motif 1DomainDomain
IPR034594 RBM12, RNA recognition motif 2DomainDomain
IPR034854 RBM12, RNA recognition motif 5DomainDomain
IPR034855 RBM12, RNA recognition motif 3DomainDomain
IPR034856 RBM12, RNA recognition motif 4DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
617629 OMIMSchizophrenia 19 (SCZD19)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility is associated with variants affecting the gene represented in this entry.