Entity Details

Primary name SLC26A1
Entity type gene
Source Source Link

Details

PrimaryID10861
RefseqGeneNG_033042
SymbolSLC26A1
Namesolute carrier family 26 member 1
Chromosome4
Location4p16.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsS26A1_HUMAN

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0008271 secondary active sulfate transmembrane transporter activity
GO:0008272 sulfate transport
GO:0015106 bicarbonate transmembrane transporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015116 sulfate transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0019531 oxalate transmembrane transporter activity
GO:0019532 oxalate transport
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

Diseases

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Disease IDSourceNameDescription
167030 OMIMNephrolithiasis, calcium oxalate (CAON)A form of nephrolithiasis, a condition in which urinary supersaturation leads to stone formation in the urinary system. Patients manifest acute renal colic with severe pain originating in the flank. Patients with small, non-obstructing stones or those with staghorn calculi may be asymptomatic. The majority of renal calculi contain calcium. CAON is characterized by calcium oxalate kidney stones. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SLC26A1ST6GAL2BioGRID, IntAct32296183 details
SLC26A1KLK6IntAct32814053 details
SLC26A1RHOUBioGRID26598620 details
SLC26A1VIRMABioGRID29507755 details