Entity Details

Primary name SYN1
Entity type gene
Source Source Link

Details

PrimaryID6853
RefseqGeneNG_008437
SymbolSYN1
Namesynapsin I
ChromosomeX
LocationXp11.3-p11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSYN1_HUMAN

GO terms

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GOName
GO:0000795 synaptonemal complex
GO:0003779 actin binding
GO:0005215 transporter activity
GO:0005524 ATP binding
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007268 chemical synaptic transmission
GO:0007269 neurotransmitter secretion
GO:0008021 synaptic vesicle
GO:0014069 postsynaptic density
GO:0019901 protein kinase binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030672 synaptic vesicle membrane
GO:0042802 identical protein binding
GO:0046928 regulation of neurotransmitter secretion
GO:0048306 calcium-dependent protein binding
GO:0048666 neuron development
GO:0048786 presynaptic active zone
GO:0050808 synapse organization
GO:0097091 synaptic vesicle clustering
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098693 regulation of synaptic vesicle cycle
GO:0098850 extrinsic component of synaptic vesicle membrane
GO:0098993 anchored component of synaptic vesicle membrane
GO:2000300 regulation of synaptic vesicle exocytosis

Diseases

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Disease IDSourceNameDescription
300491 OMIMEpilepsy X-linked, with variable learning disabilities and behavior disorders (XELBD)A neurologic disorder characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior. The disease is caused by variants affecting the gene represented in this entry.

Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
SYN1KAT5BioGRID, HPRD, IntAct16169070 details
SYN1SYN1BioGRID, HPRD, IntAct16169070 28533388 9463375 details
SYN1VIMBioGRID, HPRD, IntAct16169070 details
SYN1EGFRIntAct20029029 31980649 details
SYN1SNCABioGRID, IntAct17893145 22163275 details
SYN1RB1CC1BioGRID, MINT25640309 details
SYN1GRB2BioGRID, HPRD10899172 8022809 8552632 details
SYN1SYN2BioGRID, HPRD10358015 details
SYN1NOS1APBioGRID, HPRD11867766 details
SYN1NOS1BioGRID11867766 details
SYN1BLMBioGRID15829507 details
SYN1ITSN2BioGRID22558309 details
SYN1ERGBioGRID24591637 details
SYN1SYN3HPRD10358015 details
SYN1NCF1BioGRID, HPRD10899172 details
SYN1BIN1BioGRID, HPRD10899172 details
SYN1AMPHBioGRID, HPRD10899172 details
SYN1SRCBioGRID, HPRD10899172 details
SYN1PIK3R1BioGRID, HPRD10899172 details
SYN1CRKBioGRID, HPRD10899172 details
SYN1PRKNBioGRID11431533 details
SYN1PLCG1HPRD10899172 details
SYN1PFN2HPRD9463375 details
SYN1SPTAN1HPRD1905928 details
SYN1PRKACAHPRD10571231 12237306 details
SYN1CAMK1HPRD10571231 12237306 9395448 details
SYN1PAK2HPRD10571231 12237306 details
SYN1S100A1HPRD15147519 details
SYN1PAK1HPRD12237306 details
SYN1PAK3HPRD12237306 details
SYN1MAPK3HPRD10725920 details
SYN1CDK5HPRD8702879 details
SYN1RASA1HPRD10899172 details
SYN1ERI1BioGRID, IntAct26496610 details
SYN1ERGIC1BioGRID, IntAct26496610 details
SYN1DGCR8BioGRID, IntAct26496610 details
SYN1VPS54BioGRID, IntAct26496610 details
SYN1ANTXR1BioGRID, IntAct26496610 details
SYN1GTF3C2BioGRID, IntAct26496610 details
SYN1PSMD2BioGRID, IntAct26496610 details
SYN1ATG4ABioGRID, IntAct26496610 details
SYN1NUFIP1BioGRID, IntAct26186194 28514442 details
SYN1DGUOKBioGRID, IntAct26186194 28514442 details
SYN1HAX1BioGRID, IntAct26186194 28514442 details
SYN1ARMC1BioGRID, IntAct26186194 28514442 details
SYN1DNAAF2BioGRID, IntAct26186194 28514442 details
SYN1MAPTUniProt26402096 details
SYN1PRNPUniProt28671123 details
SYN1SNAP25MINT30610939 details
SYN1SRRTBioGRID22939629 details
SYN1DDX5BioGRID22939629 details
SYN1LUC7L3BioGRID26496610 details
SYN1SAP130BioGRID26496610 details