Entity Details

Primary name TDO2
Entity type gene
Source Source Link

Details

PrimaryID6999
RefseqGene
SymbolTDO2
Nametryptophan 2,3-dioxygenase
Chromosome4
Location4q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-03-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsT23O_HUMAN

GO terms

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GOName
GO:0004833 tryptophan 2,3-dioxygenase activity
GO:0005829 cytosol
GO:0006569 tryptophan catabolic process
GO:0016597 amino acid binding
GO:0019441 tryptophan catabolic process to kynurenine
GO:0019442 tryptophan catabolic process to acetyl-CoA
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0051289 protein homotetramerization
GO:1904842 response to nitroglycerin

Diseases

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Disease IDSourceNameDescription
600627 OMIMHypertryptophanemia (HYPTRP)An autosomal recessive condition characterized by persistent hypertryptophanemia and hyperserotoninemia. The disease is caused by variants affecting the gene represented in this entry.