Entity Details

Primary name ERI1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IV48
EntryNameERI1_HUMAN
FullName3'-5' exoribonuclease 1
TaxID9606
Evidenceevidence at protein level
Length349
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesERI1

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000738 DNA catabolic process, exonucleolytic
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0008408 3'-5' exonuclease activity
GO:0019843 rRNA binding
GO:0031047 gene silencing by RNA
GO:0031125 rRNA 3'-end processing
GO:0043022 ribosome binding
GO:0046872 metal ion binding
GO:0071204 histone pre-mRNA 3'end processing complex
GO:0071207 histone pre-mRNA stem-loop binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003034 SAP domainDomainDomain
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR013520 Exonuclease, RNase T/DNA polymerase IIIDomainDomain
IPR036361 SAP domain superfamilyFamilyHomologous superfamily
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions