Entity Details

Primary name UBA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TBC4
EntryNameUBA3_HUMAN
FullNameNEDD8-activating enzyme E1 catalytic subunit
TaxID9606
Evidenceevidence at protein level
Length463
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesUBA3

GO terms

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GOName
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0006508 proteolysis
GO:0007113 endomitotic cell cycle
GO:0016922 nuclear receptor binding
GO:0019781 NEDD8 activating enzyme activity
GO:0032446 protein modification by small protein conjugation
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0043687 post-translational protein modification
GO:0044877 protein-containing complex binding
GO:0045116 protein neddylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046982 protein heterodimerization activity
GO:0051726 regulation of cell cycle

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000594 THIF-type NAD/FAD binding foldDomainDomain
IPR014929 E2 bindingDomainDomain
IPR023318 Ubiquitin activating enzyme, alpha domain superfamilyFamilyHomologous superfamily
IPR030468 NEDD8-activating enzyme E1 catalytic subunitFamilyFamily
IPR033127 Ubiquitin-activating enzyme E1, Cys active siteSiteActive site
IPR035985 Ubiquitin-activating enzymeFamilyHomologous superfamily

Diseases

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