Entity Details

Primary name HYAL3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43820
EntryNameHYAL3_HUMAN
FullNameHyaluronidase-3
TaxID9606
Evidenceevidence at protein level
Length417
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesHYAL3

GO terms

Show/Hide Table
GOName
GO:0001552 ovarian follicle atresia
GO:0001669 acrosomal vesicle
GO:0002080 acrosomal membrane
GO:0004415 hyalurononglucosaminidase activity
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005975 carbohydrate metabolic process
GO:0006954 inflammatory response
GO:0007341 penetration of zona pellucida
GO:0009615 response to virus
GO:0030214 hyaluronan catabolic process
GO:0031410 cytoplasmic vesicle
GO:0033906 hyaluronoglucuronidase activity
GO:0046677 response to antibiotic
GO:0046718 viral entry into host cell
GO:0051216 cartilage development
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071493 cellular response to UV-B
GO:0097225 sperm midpiece
GO:2000355 negative regulation of ovarian follicle development
GO:2000368 positive regulation of acrosomal vesicle exocytosis

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasmic vesicle
Early endosome
Endoplasmic reticulum
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR018155 HyaluronidaseFamilyFamily
IPR027260 Hyaluronidase-3FamilyFamily

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
HYAL3_HUMANS22A2_HUMANBioGRID, IntAct21988832 details
HYAL3_HUMANDAB1_HUMANBioGRID, IntAct25416956 details
HYAL3_HUMANBOLL_HUMANBioGRID, IntAct32296183 details
HYAL3_HUMANKCC2A_HUMANBioGRID, IntAct32296183 details