Entity Details

Primary name SI1L3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60292
EntryNameSI1L3_HUMAN
FullNameSignal-induced proliferation-associated 1-like protein 3
TaxID9606
Evidenceevidence at protein level
Length1781
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesSIPA1L3

GO terms

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GOName
GO:0001654 eye development
GO:0001725 stress fiber
GO:0002244 hematopoietic progenitor cell differentiation
GO:0003382 epithelial cell morphogenesis
GO:0005096 GTPase activator activity
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0007010 cytoskeleton organization
GO:0016324 apical plasma membrane
GO:0045177 apical part of cell
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0061689 tricellular tight junction
GO:0090162 establishment of epithelial cell polarity
GO:0090630 activation of GTPase activity

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR000331 Rap/Ran-GAP domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR021818 Signal-induced proliferation-associated 1-like protein, C-terminalDomainDomain
IPR031204 Signal-induced proliferation-associated 1-like protein 3FamilyFamily
IPR035974 Rap/Ran-GAP superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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