Entity Details

Primary name ZBT11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95625
EntryNameZBT11_HUMAN
FullNameZinc finger and BTB domain-containing protein 11
TaxID9606
Evidenceevidence at protein level
Length1053
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesZBTB11

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006355 regulation of transcription, DNA-templated
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily
IPR041588 Integrase zinc-binding domainDomainDomain

Diseases

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Disease IDSourceNameDescription
618383 OMIMIntellectual developmental disorder, autosomal recessive 69 (MRT69)A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ZBT11_HUMANSMAD7_HUMANBioGRID, HPRD, MINT15231748 details
ZBT11_HUMANPP1A_HUMANBioGRID, IntAct22321011 details