Entity Details

Primary name KCY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30085
EntryNameKCY_HUMAN
FullNameUMP-CMP kinase
TaxID9606
Evidenceevidence at protein level
Length196
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesCMPK1

GO terms

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GOName
GO:0004127 cytidylate kinase activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0004849 uridine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006225 UDP biosynthetic process
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0009220 pyrimidine ribonucleotide biosynthetic process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0033862 UMP kinase activity
GO:0036430 CMP kinase activity
GO:0036431 dCMP kinase activity
GO:0046705 CDP biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000850 Adenylate kinase/UMP-CMP kinaseFamilyFamily
IPR006266 UMP-CMP kinaseFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR033690 Adenylate kinase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00441 GemcitabineDrugbanksmall molecule
DB00709 LamivudineDrugbanksmall molecule
DB01262 DecitabineDrugbanksmall molecule
DB03403 Cytidine-5'-MonophosphateDrugbanksmall molecule
DB03435 Uridine-5'-DiphosphateDrugbanksmall molecule
DB04444 Tetrafluoroaluminate IonDrugbanksmall molecule
DB08934 SofosbuvirDrugbanksmall molecule