Entity Details

Primary name SPB6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35237
EntryNameSPB6_HUMAN
FullNameSerpin B6
TaxID9606
Evidenceevidence at protein level
Length376
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesSERPINB6

GO terms

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GOName
GO:0002020 protease binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007605 sensory perception of sound
GO:0010951 negative regulation of endopeptidase activity
GO:0030667 secretory granule membrane
GO:0043312 neutrophil degranulation
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070821 tertiary granule membrane
GO:0071470 cellular response to osmotic stress
GO:0097180 serine protease inhibitor complex
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00055 Drotrecogin alfaDrugbankbiotech