Entity Details

Primary name CDON_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ4KMG0
EntryNameCDON_HUMAN
FullNameCell adhesion molecule-related/down-regulated by oncogenes
TaxID9606
Evidenceevidence at protein level
Length1287
SequenceStatuscomplete
DateCreated2006-05-02
DateModified2021-06-02

Ontological Relatives

GenesCDON

GO terms

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GOName
GO:0001708 cell fate specification
GO:0001934 positive regulation of protein phosphorylation
GO:0002088 lens development in camera-type eye
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007224 smoothened signaling pathway
GO:0007520 myoblast fusion
GO:0009952 anterior/posterior pattern specification
GO:0010172 embryonic body morphogenesis
GO:0014816 skeletal muscle satellite cell differentiation
GO:0021987 cerebral cortex development
GO:0043393 regulation of protein binding
GO:0043410 positive regulation of MAPK cascade
GO:0045663 positive regulation of myoblast differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051149 positive regulation of muscle cell differentiation
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:2000179 positive regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR032983 Cell adhesion molecule-related/down-regulated by oncogenesFamilyFamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
614226 OMIMHoloprosencephaly 11 (HPE11)A structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability. The disease is caused by variants affecting the gene represented in this entry.