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Entity Details
Primary name
OTUL_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q96BN8
EntryName
OTUL_HUMAN
FullName
Ubiquitin thioesterase otulin
TaxID
9606
Evidence
evidence at protein level
Length
352
SequenceStatus
complete
DateCreated
2006-11-28
DateModified
2021-06-02
Ontological Relatives
Genes
OTULIN
GO terms
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GO
Name
GO:0002040
sprouting angiogenesis
GO:0004843
thiol-dependent deubiquitinase
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0008234
cysteine-type peptidase activity
GO:0010803
regulation of tumor necrosis factor-mediated signaling pathway
GO:0016055
Wnt signaling pathway
GO:0016567
protein ubiquitination
GO:0032088
negative regulation of NF-kappaB transcription factor activity
GO:0045087
innate immune response
GO:0050728
negative regulation of inflammatory response
GO:0060828
regulation of canonical Wnt signaling pathway
GO:0070431
nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0071797
LUBAC complex
GO:1990108
protein linear deubiquitination
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR023235
FAM105
Family
Family
IPR023237
Ubiquitin thioesterase otulin
Family
Family
Diseases
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Drugs
Show/Hide Table
Interactions
23 interactions
Interactor
Partner
Sources
Publications
Link
OTUL_HUMAN
DVL2_HUMAN
BioGRID, HPRD, IntAct
16189514
23708998
details
OTUL_HUMAN
DAZP2_HUMAN
BioGRID, IntAct
25416956
32296183
details
OTUL_HUMAN
F168A_HUMAN
BioGRID, IntAct
25416956
32296183
details
OTUL_HUMAN
TM239_HUMAN
BioGRID, IntAct
32296183
details
OTUL_HUMAN
OTU7B_HUMAN
BioGRID, IntAct
32296183
details
OTUL_HUMAN
SFT2A_HUMAN
BioGRID, IntAct
32296183
details
OTUL_HUMAN
SUSD6_HUMAN
BioGRID, IntAct
32296183
details
OTUL_HUMAN
SPART_HUMAN
BioGRID, IntAct
32296183
details
OTUL_HUMAN
UBC_HUMAN
BioGRID
23708998
23746843
23827681
24726327
25527291
28319114
28919039
29576527
31056421
31541095
details
OTUL_HUMAN
RNF31_HUMAN
BioGRID
23708998
24726323
24726327
26670046
27307491
27458237
27545878
27591049
28189684
28244869
28919039
31504727
31541095
33329596
details
OTUL_HUMAN
TERA_HUMAN
BioGRID
24726323
31541095
details
OTUL_HUMAN
BCL10_HUMAN
BioGRID
27777308
details
OTUL_HUMAN
SPAT2_HUMAN
BioGRID
27545878
details
OTUL_HUMAN
SNX27_HUMAN
BioGRID
31541095
details
OTUL_HUMAN
OTUL_HUMAN
BioGRID
31504727
details
OTUL_HUMAN
SHRPN_HUMAN
BioGRID
23746843
24726323
26670046
27591049
28919039
details
OTUL_HUMAN
HOIL1_HUMAN
BioGRID
23708998
24726323
24726327
26670046
28919039
31504727
details
OTUL_HUMAN
TNFA_HUMAN
BioGRID
24726327
27307491
details
OTUL_HUMAN
BOP1_HUMAN
BioGRID
25825154
details
OTUL_HUMAN
TRI32_HUMAN
BioGRID
31504727
details
OTUL_HUMAN
STAT1_HUMAN
BioGRID
32123171
details
OTUL_HUMAN
ATG13_HUMAN
BioGRID
32543267
details
OTUL_HUMAN
MALT1_HUMAN
BioGRID
33329596
details
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