Entity Details
| Primary name |
APOL1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | O14791 |
| EntryName | APOL1_HUMAN |
| FullName | Apolipoprotein L1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 398 |
| SequenceStatus | complete |
| DateCreated | 1998-07-15 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Secreted |
Domains
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| Domain | Name | Category | Type |
| IPR008405 | Apolipoprotein L | Family | Family |
Diseases
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| Disease ID | Source | Name | Description |
| 612551 | OMIM | Focal segmental glomerulosclerosis 4 (FSGS4) | A renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and progressive decline in renal function. Renal insufficiency often progresses to end-stage renal disease, a highly morbid state requiring either dialysis therapy or kidney transplantation. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB01593 | Zinc | Drugbank | small molecule |
| DB14487 | Zinc acetate | Drugbank | small molecule |
| DB14533 | Zinc chloride | Drugbank | small molecule |
| DB14548 | Zinc sulfate, unspecified form | Drugbank | small molecule |
Interactions
3 interactions